Evidence map›Paper›PMID 27470303›Full record

ArticleImmunologic research2017

A novel bedside test for ACPA: the CCPoint test is moving the laboratory to the rheumatologist's office.

Gisele Zandman-Goddard, Alessandra Soriano, Boris Gilburd, Merav Lidar, Shaye Kivity, Ron Kopilov, Pnina Langevitz, Yehuda Shoenfeld, Nancy Agmon-Levin

Erratum issuedAbstract read
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In one paragraph

Article in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Gisele Zandman-GoddardZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Alessandra SorianoZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Boris GilburdZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Merav LidarSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shaye KivitySackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ron KopilovZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Pnina LangevitzSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yehuda ShoenfeldZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Nancy Agmon-LevinZabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel. nancy.agmon-levin@sheba.health.gov.il.
Sheba Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid Arthritis (RA) is an autoimmune destructive joint disease affecting 1 % of the general population. In recent years, the benefits of identifying RA at an early stage and initiating therapy before joint damage occurs have been acknowledged. An elevated anti-citrullinated peptide antibody (ACPA) level serves as a marker for the early diagnosis of RA. Often the diagnosis is delayed because conventional methods of antibody detection require referral to a specific laboratory. In the current study, we determined the diagnostic accuracy of a new lateral flow point-of-care kit available for ACPA detection in the rheumatologist office. The presence of ACPA was determined by the visually read, qualitative rapid CCPoint

Indexed as

Point-of-Care TestingAdultAgedAnti-Citrullinated Protein AntibodiesArthritis, RheumatoidBiomarkersEarly DiagnosisEnzyme-Linked Immunosorbent AssayFemaleHumansLupus Erythematosus, SystemicMaleMiddle AgedRheumatologistsSensitivity and SpecificitySerumAnti-Citrullinated Protein AntibodiesBiomarkersACPACCPoint testDiagnosticsPOCRheumatoid arthritis

Identifiers

PMID27470303
OpenAlexW4232999107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.