Evidence map›Paper›PMID 27470211›Full record

ArticleBMB reports2016

Analysis of extended haplotype in Korean cattle (Hanwoo) population.

Dajeong Lim, Bong Hwan Choi, Yong Min Cho, Han Ha Chai, Gul Won Jang, Cedric Gondro, Yeoung Ho Jeoung, Seung Hwan Lee

Open access · goldAbstract read
In one paragraph

Article in BMB reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dajeong LimDivision of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Jeonju 55365, Korea.
Bong Hwan ChoiDivision of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Jeonju 55365, Korea.
Yong Min ChoDivision of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Jeonju 55365, Korea.
Han Ha ChaiDivision of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Jeonju 55365, Korea.
Gul Won JangDivision of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Jeonju 55365, Korea.
Cedric GondroSchool of Environmental and Rural Science, University of New England, Armidale, NSW 2351, Australia.
Yeoung Ho JeoungHanwoo Department, Korea Animal Improvement Association, Seoul 06668, Korea.
Seung Hwan LeeDivision of Animal and Dairy Science, Chung Nam National University, Daejeon 34134, Korea.
University of New England · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Korean cattle (Hanwoo) are categorized into three breeds based on color: brown, brindle, and black. Among these breeds, brown Hanwoo has been subjected to intensive selection to improve meat traits. To identify genetic traces driven by recent selection in brown Hanwoo, we scanned the genomes of brown and brindle Hanwoo using a bovine SNP chip. We identified 17 candidate selection signatures in brown Hanwoo and sequenced four candidate regions from 10 individuals each of brown and brindle Hanwoo. In particular, non-synonymous SNPs in the ADSL gene (K88M, L189H, and R302Q) might have had mutational effects on protein structure as a result of altering the purine pathway during nucleotide breakdown. The ADSL gene was previously reported to affect meat quality and yield in livestock. Meat quality and yield are main breeding goals for brown Hanwoo, and our results support a potential causal influence of non-synonymous SNPs in the ADSL gene. [BMB Reports 2016; 49(9): 514-519].

Indexed as

GenomeAdenylosuccinate LyaseAnimalsBreedingCattleGenotypeHaplotypesHomozygoteMeatPolymorphism, Single NucleotidePrincipal Component AnalysisRepublic of KoreaSequence Analysis, DNAAdenylosuccinate Lyase

Identifiers

PMID27470211
PMCPMC5227145
OpenAlexW2488865721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.