Evidence map›Paper›PMID 27469506›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017

The challenge of measuring intra-individual change in fatigue during cancer treatment.

Carol M Moinpour, Gary W Donaldson, Kimberly M Davis, Arnold L Potosky, Roxanne E Jensen, Julie R Gralow, Anthony L Back, Jimmy J Hwang, Jihye Yoon, Debra L Bernard and 7 more

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Patient-Reported Outcomes Measurement Information System in patients with gastrointestinal cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  3. Likely change indexes improve estimates of individual change on patient-reported outcomes.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  4. Between-group minimally important change versus individual treatment responders.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Carol M MoinpourPublic Health Sciences Division, Fred Hutchinson Cancer Research Center [Emerita], Seattle, WA, USA. cmoinpou@fredhutch.org.
Gary W DonaldsonPain Research Center, Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA.
Kimberly M DavisHealth Services Research, Georgetown University Medical Center, and Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Arnold L PotoskyHealth Services Research, Georgetown University Medical Center, and Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Roxanne E JensenHealth Services Research, Georgetown University Medical Center, and Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Julie R GralowSeattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Anthony L BackSeattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Jimmy J HwangHematology/Oncology, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC, USA.
Jihye YoonCancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Debra L BernardSeattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Deena R LoefflerThe Cystic Fibrosis Foundation, Bethesda, MD, USA.
Nan E RothrockDepartment of Medical Social Sciences and Center for Patient-Centered Outcomes, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ron D HaysDepartments of Medicine and Health Services Research, University of California Los Angeles, Los Angeles, CA, USA.
Bryce B ReeveDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ashley Wilder SmithOutcomes Research Branch, National Cancer Institute, Bethesda, MD, USA.
Elizabeth A HahnDepartment of Medical Social Sciences and Center for Patient-Centered Outcomes, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
David CellaDepartment of Medical Social Sciences and Center for Patient-Centered Outcomes, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Validating and Extending the PROMIS Sexual Function Measure for Clinical ResearchU01AR052186 · NIAMS · DUKE UNIVERSITY · PI WEINFURT, KEVIN P · 2004 to 2013
$9.5M
PROMIS Pediatrics: Longitudinal Validation and Linking Pediatric and Adult Item BU01AR052181 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI REEVE, BRYCE B · 2004 to 2013
$9.1M
Patient reported outcomes in routine clinical care of patients infected with HIVU01AR057954 · NIAMS · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., CRANE, PAUL K · 2009 to 2013
$7.8M
Institutional Career Development CoreKL2TR001432 · NCATS · GEORGETOWN UNIVERSITY · PI UMANS, JASON G · 2015 to 2024
$7.5M
Validation and domain development in mental health and sleep-wake functionU01AR052155 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PILKONIS, PAUL A · 2004 to 2013
$6.0M
Validation of PROMIS in Diverse Cancer PopulationsU01AR057971 · NIAMS · GEORGETOWN UNIVERSITY · PI MOINPOUR, CAROL M, POTOSKY, ARNOLD L · 2009 to 2013
$5.7M
Improving Assessment of Physical Function and Drug Safety in Health and DiseaseU01AR052158 · NIAMS · STANFORD UNIVERSITY · PI KRISHNAN, ESWAR · 2004 to 2013
$5.6M
PROMIS Technical CenterU54AR057943 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GERSHON, RICHARD · 2009 to 2013
$5.3M
UW Center on Outcomes Research in Rehabilitation(RMI)U01AR052171 · NIAMS · UNIVERSITY OF WASHINGTON · PI AMTMANN, DAGMAR · 2004 to 2008
$5.0M
Pediatric PROMIS: Advancing the Measurement and Conceptualizaiton of Child HealthU01AR057956 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI FORREST, CHRISTOPHER B · 2009 to 2014
$4.9M
PROMIS Statistical CenterU54AR057951 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2009 to 2014
$3.6M
NCATS NIH HHS KL2 TR001432NCI NIH HHS P30 CA060553NIAMS NIH HHS U01 AR052155NIAMS NIH HHS U01 AR052158NIAMS NIH HHS U01 AR052171NIAMS NIH HHS U01 AR052181NIAMS NIH HHS U01 AR052186NIAMS NIH HHS U01 AR057929NIAMS NIH HHS U01 AR057936NIAMS NIH HHS U01 AR057940NIAMS NIH HHS U01 AR057948NIAMS NIH HHS U01 AR057954NIAMS NIH HHS U01 AR057956NIAMS NIH HHS U01 AR057967NIAMS NIH HHS U01 AR057971NIAMS NIH HHS U54 AR057926NIAMS NIH HHS U54 AR057943NIAMS NIH HHS U54 AR057951
6 · The paper itself

Abstract

purposeTo evaluate how well three different patient-reported outcomes (PROs) measure individual change.

methodsTwo hundred and fourteen patients (from two sites) initiating first or new chemotherapy for any stage of breast or gastrointestinal cancer participated. The 13-item FACIT Fatigue scale, a 7-item PROMIS

resultsA linear model for measured change showed the following by 6 and 3 months, respectively: PROMIS CAT (0.363 and 0.342); PROMIS SF (0.408 and 0.533); FACIT (0.459 and 0.473). Quadratic models offered no noteworthy improvement over linear models. Both reliability and precision results demonstrate the need to improve the measurement of intra-individual change.

conclusionsThese results illustrate the challenge of reliably measuring individual change in fatigue with a level of confidence required for intervention. Optimizing clinically useful measurement of intra-individual differences over time continues to pose a challenge for PROs.

Indexed as

Patient Reported Outcome MeasuresFatigueFemaleHumansMiddle AgedNeoplasmsQuality of LifeSurveys and QuestionnairesCancerFatigueIntra-individual changeMeasured changePatient-reported outcomes

Identifiers

PMID27469506
PMCPMC5274585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.