ReviewDong wu xue yan jiu = Zoological research2016
Modeling postpartum depression in rats: theoretic and methodological issues.
Review in Dong wu xue yan jiu = Zoological research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Distal pup cues attenuate defensive reactivity and fear-potentiated startle magnitude in postpartum rats without altering sensorimotor gating.Behavioral neuroscience · 2026Article
- Gestational stress disrupts the neuroimmune environment in the nucleus accumbens of maternal rats.Brain, behavior, & immunity - health · 2025Article
- Gestational stress disrupts dopamine and oxytocin signaling in the postpartum reward system of rats: implications for mood, motivation and mothering.Scientific reports · 2025Article
- Bridging Neurobiological Insights and Clinical Biomarkers in Postpartum Depression: A Narrative Review.International journal of molecular sciences · 2024Review
- Long-term impacts of prenatal maternal immune activation and postnatal maternal separation on maternal behavior in adult female rats: Relevance to postpartum mental disorders.Behavioural brain research · 2024Article
- Assessing cognitive biases induced by acute formalin or hotplate treatment: an animal study using affective bias test.Frontiers in behavioral neuroscience · 2024Article
- Lateral habenula neurocircuits mediate the maternal disruptive effect of maternal stress: A hypothesis.Zoological research · 2022Review
- Evidence of Anxiety, Depression and Learning Impairments following Prenatal Hypertension.Behavioral sciences (Basel, Switzerland) · 2022Article
- Experience-Regulated Neuronal Signaling in Maternal Behavior.Frontiers in molecular neuroscience · 2022Review
- Postpartum scarcity-adversity disrupts maternal behavior and induces a hypodopaminergic state in the rat dam and adult female offspring.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Dopamine downregulation in novel rodent models useful for the study of postpartum depression.Frontiers in behavioral neuroscience · 2022Article
- Immune System Alterations and Postpartum Mental Illness: Evidence From Basic and Clinical Research.Frontiers in global women's health · 2021Review
- The Prolactin Family of Hormones as Regulators of Maternal Mood and Behavior.Frontiers in global women's health · 2021Review
- Maternal Separation Model of Postpartum Depression: Potential Role for Nucleus Accumbens Dopamine D1-D2 Receptor Heteromer.Neurochemical research · 2020Article
- Adaptations in reward-related behaviors and mesolimbic dopamine function during motherhood and the postpartum period.Frontiers in neuroendocrinology · 2020Review
- Chronic psychosocial stress during pregnancy affects maternal behavior and neuroendocrine function and modulates hypothalamic CRH and nuclear steroid receptor expression.Translational psychiatry · 2020Article
- The maternal reward system in postpartum depression.Archives of women's mental health · 2019Review
- Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression.Evidence-based complementary and alternative medicine : eCAM · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adaptions is thought to contribute to disruptions of emotion regulation, motivation and cognitive abilities that underlie postpartum mental disorders, such as postpartum depression. Despite the high incidence of this disorder, and the detrimental consequences for both mother and child, its etiology and related neurobiological mechanisms remain poorly understood, partially due to the lack of appropriate animal models. In recent decades, there have been a number of attempts to model postpartum depression disorder in rats. In the present review, we first describe clinical symptoms of postpartum depression and discuss known risk factors, including both genetic and environmental factors. Thereafter, we discuss various rat models that have been developed to capture various aspects of this disorder and knowledge gained from such attempts. In doing so, we focus on the theories behind each attempt and the methods used to achieve their goals. Finally, we point out several understudied areas in this field and make suggestions for future directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.