Trial reportScientific reports2016
The Frequency and Energy of Snoring Sounds Are Associated with Common Carotid Artery Intima-Media Thickness in Obstructive Sleep Apnea Patients.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Obstructive Sleep Apnea Risk and Incidental Coronary Artery Calcification on Routine Chest Computed Tomography.Journal of clinical medicine · 2026Article
- Article
- Is There Any Relationship Between Primary Snoring and Carotid Intima-Media Thickness? A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Snoring sound classification in patients with cerebrovascular stenosis based on an improved ConvNeXt model.Frontiers in physiology · 2025Article
- Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ.Journal of inflammation (London, England) · 2023Review
- Combined Airway and Bariatric Surgery (CABS) for Obstructive Sleep Apnea Patients with Morbid Obesity: A Comprehensive Alternative Preliminary Study.Journal of clinical medicine · 2022Article
- Obstructive Sleep Apnea and Auditory Dysfunction-Does Snoring Sound Play a Role?Diagnostics (Basel, Switzerland) · 2022Article
- Validation of snoring detection using a smartphone app.Sleep & breathing = Schlaf & Atmung · 2022Article
- Long-term benefits of a new oral appliance on adult snoring: a trend analysis.Multidisciplinary respiratory medicine · 2022Article
- Respiratory Motion and Airflow Estimation During Sleep Using Tracheal Movement and Sound.Nature and science of sleep · 2022Article
- Screening Severe Obstructive Sleep Apnea in Children with Snoring.Diagnostics (Basel, Switzerland) · 2021Article
- Automatic classification of excitation location of snoring sounds.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Snoring severity is associated with carotid vascular remodeling in young adults with overweight and obesity.Sleep health · 2021Article
- Snoring Sound Characteristics are Associated with Common Carotid Artery Profiles in Patients with Obstructive Sleep Apnea.Nature and science of sleep · 2021Article
- Assessment of atherosclerotic plaque activity in patients with sleep apnea using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI): a feasibility study.Sleep & breathing = Schlaf & Atmung · 2018Article
- Numerical study of dynamic glottis and tidal breathing on respiratory sounds in a human upper airway model.Sleep & breathing = Schlaf & Atmung · 2018Article
- Association between Snoring and High-Risk Carotid Plaque Features.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is a known risk factor for atherosclerosis. We investigated the association of common carotid artery intima-media thickness (CCA-IMT) with snoring sounds in OSA patients. A total of 30 newly diagnosed OSA patients with no history of cardiovascular diseases were prospectively enrolled for measuring mean CCA-IMT with B-mode ultrasonography, body mass index, metabolic syndrome, 10-year cardiovascular disease risk score, high-sensitivity C-reactive protein, and homocysteine. Good-quality signals of full-night snoring sounds in an ordinary sleep condition obtained from 15 participants were further acoustically analyzed (Included group). All variables of interest were not significantly different (all p > 0.05) between the included and non-included groups except for diastolic blood pressure (p = 0.037). In the included group, CCA-IMT was significantly correlated with snoring sound energies of 0-20 Hz (r = 0.608, p = 0.036) and 652-1500 Hz (r = 0.632, p = 0.027) and was not significantly associated with that of 20-652 Hz (r = 0.366, p = 0.242) after adjustment for age and sex. Our findings suggest that underlying snoring sounds may cause carotid wall thickening and support the large-scale evaluation of snoring sound characters as markers of surveillance and for risk stratification at diagnosis.
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