Evidence map›Paper›PMID 27469183›Full record

ReviewPediatric clinics of North America2016

Endocrine Disorders in Cystic Fibrosis.

Scott M Blackman, Vin Tangpricha

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04379726 (Characterization of β-cell Function and Insulin Sensitivity in Pre-transplant Patients With Cystic Fibrosis), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04379726 unknown statusnot on this mapstarted 2020, after this paper: background citation

Characterization of β-cell Function and Insulin Sensitivity in Pre-transplant Patients With Cystic Fibrosis

TypeobservationalSponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoRan2020 to 2023Enrolled150ConditionsCystic Fibrosis-related DiabetesArmstherapeutic optimization
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. An update on methods for assessing bone quality and health in Cystic fibrosis.Journal of clinical & translational endocrinology · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. GH-IGF-1 Axis in Children with Cystic Fibrosis.Clinical medicine & research · 2019
    Article
  19. Article
  20. Gender differences in bronchiectasis: a real issue?Breathe (Sheffield, England) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Scott M BlackmanDivision of Pediatric Endocrinology, Department of Pediatrics, Johns Hopkins Hospital, Johns Hopkins University, 200 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address: sblackman@jhmi.edu.
Vin TangprichaDivision of Endocrinology, Metabolism and Lipids, Department of Medicine, Atlanta VA Medical Center, Emory University School of Medicine, 101 Woodruff Circle NE, WMRB1301, Atlanta, GA 30322, USA.
Emory University · USJohns Hopkins University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001079
6 · The paper itself

Abstract

Cystic fibrosis is frequently complicated by endocrine disorders. Diabetes can be expected to affect most with CF and pancreatic insufficiency and varies widely in age of onset, but early identification and treatment improve morbidity and mortality. Short stature can be exacerbated by relative delay of puberty and by use of inhaled corticosteroids. Bone disease in CF causes fragility fractures and should be assessed by monitoring bone mineral density and optimizing vitamin D status. Detecting and managing endocrine complications in CF can reduce morbidity and mortality in CF. These complications can be expected to become more common as the CF population ages.

Indexed as

Cystic FibrosisEndocrine System DiseasesFemaleHumansMaleDiabetesHypoglycemiaHypogonadismOsteoporosisShort stature

Identifiers

PMID27469183
PMCPMC5354098
OpenAlexW2494411494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.