Evidence map›Paper›PMID 27469173›Full record

ArticlePublic health nutrition2017

Effect of waist circumference on the association between serum 25-hydroxyvitamin D and serum lipids: results from the National Health and Nutrition Examination Survey 2001-2006.

Susanne Vogt, Jens Baumert, Annette Peters, Barbara Thorand, Robert Scragg

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Susanne Vogt1Institute of Epidemiology II,Helmholtz Zentrum München,German Research Center for Environmental Health,Ingolstädter Landstraße 1,85764 Neuherberg,Germany.
Jens Baumert1Institute of Epidemiology II,Helmholtz Zentrum München,German Research Center for Environmental Health,Ingolstädter Landstraße 1,85764 Neuherberg,Germany.
Annette Peters1Institute of Epidemiology II,Helmholtz Zentrum München,German Research Center for Environmental Health,Ingolstädter Landstraße 1,85764 Neuherberg,Germany.
Barbara Thorand1Institute of Epidemiology II,Helmholtz Zentrum München,German Research Center for Environmental Health,Ingolstädter Landstraße 1,85764 Neuherberg,Germany.
Robert Scragg4Section of Epidemiology and Biostatistics,School of Population Health,University of Auckland,Auckland,New Zealand.
Helmholtz Zentrum München · DEDeutsches Diabetes-Zentrum e.V. · DEGerman Centre for Cardiovascular Research · DEUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the interaction between waist circumference (WC) and serum 25-hydroxyvitamin D (25(OH)D) level in their associations with serum lipids.

designCross-sectional study. The associations of serum 25(OH)D with total cholesterol, HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), LDL-C:HDL-C and TAG were examined using multiple linear regression. Effect modification by WC was assessed through cross-product interaction terms between 25(OH)D and WC categories (abdominal overweight, 80-<88 cm in females/94-<102 cm in males; abdominal obesity, ≥88 cm in females/≥102 cm in males).

settingThe US National Health and Nutrition Examination Survey waves 2001-2006. SUBJECTS: Non-pregnant fasting participants (n 4342) aged ≥20 years.

resultsLower 25(OH)D levels were significantly associated with lower HDL-C levels as well as with higher LDL-C:HDL-C and TAG levels in abdominally obese participants, but not in abdominally overweight or normal-waist participants. In contrast, lower 25(OH)D levels were associated with lower levels of total cholesterol and LDL-C in abdominally overweight and normal-waist participants only, but this association was only partly significant. However, a significant difference in the association between 25(OH)D and the lipids according to WC category was found only for LDL-C:HDL-C (P for interaction=0·02).

conclusionsOur results from this large, cross-sectional sample suggest that the association between lower 25(OH)D levels and an unfavourable lipid profile is stronger in individuals with abdominal obesity than in those with abdominal overweight or a normal WC.

Indexed as

Waist CircumferenceAdultAgedCross-Sectional StudiesFemaleHumansLipidsMaleMiddle AgedNutrition SurveysUnited StatesVitamin DYoung Adult25-hydroxyvitamin DLipidsVitamin DInteractionNHANESSerum lipidsVitamin DWaist circumference

Identifiers

PMID27469173
PMCPMC10261314
OpenAlexW2499006210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.