ReviewJournal of the American Society of Nephrology : JASN2016
Acidosis and Urinary Calcium Excretion: Insights from Genetic Disorders.
Review in Journal of the American Society of Nephrology : JASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society.European journal of nutrition · 2023Pooled it
- Impact of Intestinal Urinary Diversion on the Risk of Fracture and Loss of Bone Mass: A Systematic Review.Bladder cancer (Amsterdam, Netherlands) · 2021Pooled it
- Resolving cell-cell interaction networks and their molecular logic in complex tissues.Nature methods · 2026Article
- Strategies for Managing Fluids and Electrolytes in High-Output Stomas: A Systematic Review and Evidence Summary.Journal of multidisciplinary healthcare · 2026Review
- Sjogren Disease and Nephrolithiasis: A Case Series and Review of the Literature.Clinics and practice · 2025Article
- Apparent digestibility and calcium and phosphorus in urine after feeding different combinations of calcium and phosphorus sources to adult dogs.Journal of animal physiology and animal nutrition · 2025Article
- Primary Distal Renal Tubular Acidosis: Toward an Optimal Correction of Metabolic Acidosis.Clinical journal of the American Society of Nephrology : CJASN · 2024Review
- Calcium signalling and transport in the kidney.Nature reviews. Nephrology · 2024Review
- Article
- Recent advances in acid sensing by G protein coupled receptors.Pflugers Archiv : European journal of physiology · 2024Review
- Effect of Feeding a Calcium Chloride Supplement on Sow Stillbirth Rate.Animals : an open access journal from MDPI · 2024Article
- Treatment of experimental hyperchloremic metabolic acidosis in horses with enteral electrolyte solution containing sodium acetate.Frontiers in veterinary science · 2024Article
- Renal calcification in children with renal tubular acidosis: What a paediatrician should know.World journal of clinical pediatrics · 2023Review
- Gamma-glutamyl transferase and calculus of kidney incidence: a Mendelian randomization study.Scientific reports · 2023Article
- Association of serum bicarbonate with the development of kidney stones in patients with chronic kidney disease: a retrospective cohort study.Clinical kidney journal · 2023Article
- Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells.Clinical and experimental pharmacology & physiology · 2023Article
- Structural and functional understanding of disease-associated mutations in V-ATPase subunit a1 and other isoforms.Frontiers in molecular neuroscience · 2023Review
- Bone metabolism during strict head-down tilt bed rest and exposure to elevated levels of ambient CONPJ microgravity · 2022Article
- Molecular mechanisms altering tubular calcium reabsorption.Pediatric nephrology (Berlin, Germany) · 2022Review
- Distal Renal Tubular Acidosis Associated with Autoimmune Diseases: Reports of 3 Cases and Review of Mechanisms.The American journal of case reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic acidosis is associated with increased urinary calcium excretion and related sequelae, including nephrocalcinosis and nephrolithiasis. The increased urinary calcium excretion induced by metabolic acidosis predominantly results from increased mobilization of calcium out of bone and inhibition of calcium transport processes within the renal tubule. The mechanisms whereby acid alters the integrity and stability of bone have been examined extensively in the published literature. Here, after briefly reviewing this literature, we consider the effects of acid on calcium transport in the renal tubule and then discuss why not all gene defects that cause renal tubular acidosis are associated with hypercalciuria and nephrocalcinosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.