Evidence map›Paper›PMID 27468917›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017

Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice.

Nora M McCall, Lydia Kotecki, Sergio Dominguez-Lopez, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Amanda L Sharpe, Michael J Beckstead, Kevin Wickman

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Motor-to-Limbic Design of Direct Synaptic Communication between Dopamine Neurons in the Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Neurotensin Release from Dopamine Neurons Drives Long-Term Depression of Substantia Nigra Dopamine Signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  14. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  15. Article
  16. Complexes of Ghrelin GHS-R1a, GHS-R1b, and Dopamine DThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  17. Article
  18. Article
  19. Potassium Channels and Their Potential Roles in Substance Use Disorders.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nora M McCallGraduate Program in Neuroscience, University of Minnesota, Minneapolis, MN, USA.
Lydia KoteckiDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, USA.
Sergio Dominguez-LopezDepartment of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Ezequiel Marron Fernandez de VelascoDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, USA.
Nicholas CarlblomDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, USA.
Amanda L SharpeDepartment of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Michael J BecksteadDepartment of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Kevin WickmanDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-5179-9540
University of Minnesota · USThe University of Texas Health Science Center at San Antonio · US

Funding

NEUROSCIENCE TRAINING IN DRUG ABUSE RESEARCHT32DA007234 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Paul G Mermelstein, Jocelyn M Richard · 1986 to 2026
$10.9M
PREDOCTORAL TRAINING OF NEUROSCIENTISTST32GM008471 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EBNER, TIMOTHY J · 1993 to 2017
$4.9M
G protein-gated K+ channels and inhibitory signalingR01MH061933 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI WICKMAN, KEVIN D · 2001 to 2016
$4.4M
Relevance and plasticity of inhibitory metabotropic signaling in reward circuitsR01DA034696 · NIDA · UNIVERSITY OF MINNESOTA · PI WICKMAN, KEVIN D · 2013 to 2022
$3.4M
The role of dendrodendritic dopamine neurotransmission in methamphetamine abuseR01DA032701 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BECKSTEAD, MICHAEL J · 2013 to 2017
$1.7M
Cocaine-induced adaptations in inhibitory signaling in VTA dopamine neuronsF31DA041767 · NIDA · UNIVERSITY OF MINNESOTA · PI MCCALL, NORA · 2016 to 2018
$116k
NIDA NIH HHS F31 DA041767NIDA NIH HHS R01 DA032701NIDA NIH HHS R01 DA034696NIDA NIH HHS T32 DA007234NIGMS NIH HHS T32 GM008471NIMH NIH HHS R01 MH061933
6 · The paper itself

Abstract

The increase in dopamine (DA) neurotransmission stimulated by in vivo cocaine exposure is tempered by G protein-dependent inhibitory feedback mechanisms in DA neurons of the ventral tegmental area (VTA). G protein-gated inwardly rectifying K

Indexed as

RewardAnimalsBehavior, AnimalCocaineDopaminergic NeuronsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsLearningMiceMice, TransgenicReceptors, Dopamine D2Ventral Tegmental AreaCocaineDRD2 protein, mouseG Protein-Coupled Inwardly-Rectifying Potassium ChannelsKcnj6 protein, mouseReceptors, Dopamine D2

Identifiers

PMID27468917
PMCPMC5240170
OpenAlexW2498393755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.