Evidence map›Paper›PMID 27468735›Full record

SynthesisJournal of anesthesia2016

Finer gauge of cutting but not pencil-point needles correlate with lower incidence of post-dural puncture headache: a meta-regression analysis.

Andres Zorrilla-Vaca, Ryan Healy, Carolina Zorrilla-Vaca

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Journal of anesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Recent Advances in Smart Epidural Spinal Needles.Sensors (Basel, Switzerland) · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. PNEUMOCEPHALUS: IS THE NEEDLE SIZE SIGNIFICANT?Innovations in clinical neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Andres Zorrilla-VacaDepartment of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, 1800 Orleans Street, Sheikh Zayed Tower 3014C, Baltimore, MD, 21287, USA. azorrilla1@jhmi.edu.ORCID 0000-0001-8140-8486
Ryan HealyDepartment of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, 1800 Orleans Street, Sheikh Zayed Tower 3014C, Baltimore, MD, 21287, USA.
Carolina Zorrilla-VacaFaculty of Health, Universidad Libre, Cali, Colombia.
Johns Hopkins Hospital · USUniversidad Libre de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePost-dural puncture headache (PDPH) is a well-known neurological outcome caused by leakage of cerebrospinal fluid during neuraxial anesthesia. Studies aimed at assessing the efficacy of finer gauged spinal needles to reduce the incidence of PDPH have produced conflicting results. We have therefore examined the effect of the gauge of cutting needles and pencil-point needles, separately, on the incidence of PDPH.

methodsThe PubMed, EMBASE and Google Scholar databases were searched for randomized studies which compared PDPH incidence in a head-to-head analysis of individual needle gauges of similar needle designs (cutting and pencil-point). A meta-regression analysis was performed taking into account various covariates, such as needle gauge and design, mean age of patient population, surgery type, percentage of males and females in study population and year of publication.

resultsOf the 22 studies (n = 5631) included in the analysis, 12 (n = 3148) and ten (n = 2483) compared different gauges of cutting needles and pencil-point needles, respectively. After adjusting for covariates, meta-regression analysis was performed for all studies that randomly compared individual needle gauges of similar needle design. Whereas the incidence of PDPH inversely correlated with gauge in cutting needles (β = -1.36 % per gauge, P = 0.037), no relationship was noted in pencil-point needles (β = -0.32 % per gauge, P = 0.114). Female gender was the only covariate that reached a statistically significant correlation with the incidence of PDPH in both models.

conclusionsA significant relationship between needle gauge and subsequent rate of PDPH was noted in cutting needles, but not pencil-point needles.

Indexed as

NeedlesAnesthesia, SpinalHumansIncidencePost-Dural Puncture HeadacheSpinal PuncturePatient safetyPost-dural puncture headacheSpinal anesthesiaSpinal needle

Identifiers

PMID27468735
OpenAlexW2498155948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.