ReviewClinical hypertension2016
Hypertensive response to exercise: mechanisms and clinical implication.
Review in Clinical hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Brazilian Guideline for Exercise Test in the Adult Population - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- The association of smoothness index of central blood pressure with ambulatory carotid femoral pulse wave velocity after 20-week treatment with losartan in combination with amlodipine versus hydrochlorothiazide.Journal of hypertension · 2019Trial
- Impact of physical activity patterns on major adverse cardiovascular events in adults with hypertension.British journal of sports medicine · 2026Article
- Reference Standards for Blood Pressure Response During Peak Exercise in Pediatric Patients with Structurally Normal Hearts.Pediatric cardiology · 2026Article
- Proteomic Risk Score for Prediction of Incident Hypertension.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Exercise-induced hypertension, atherogenic lipid subfractions, and cardiorespiratory fitness in marathon runners.Preventive medicine reports · 2026Article
- Weekend warriors, physical activity pattern and all-cause mortality: a prospective study of 150,145 Mexican adults with and without hypertension.BMC public health · 2025Article
- Navigating atrial fibrillation in an endurance athlete: Evaluation, risk stratification, lifestyle modifications, and therapeutic considerations.HeartRhythm case reports · 2025Article
- Evaluating Blood Pressure Response Patterns to Exercise Stress Testing.Hypertension (Dallas, Tex. : 1979) · 2025Article
- The acute impact of resistance exercise training on cardiovascular parameters in trained and untrained adults with high blood pressure.European journal of applied physiology · 2025Article
- Effects of Acute Exercise Bouts on Cardiovascular Biomarkers in Runners with Exercise-Induced Hypertension.Sports (Basel, Switzerland) · 2025Article
- Short-term disruption of TGF-β signaling in adult mice renders the aorta vulnerable to hypertension-induced dissection.JCI insight · 2025Article
- Mild hyperbaric hyperoxia improves aerobic capacity and suppresses cardiopulmonary stress during the maximal cycle-ergometer test.PloS one · 2025Article
- Association Between Recovery Systolic Blood Pressure After Spot Marching Exercise and Vascular Function in Middle-Aged Adults.Vascular health and risk management · 2025Article
- Association Between Metabolic Syndrome and Cardiac Autonomic Nervous Function and Cardiorespiratory Fitness in Older Adults: A Retrospective Observational Study with Propensity Score Overlap Weighting.Clinical interventions in aging · 2025Observational
- Hypertensive Response to Exercise as an Early Marker of Disease Development.Biomedicines · 2024Review
- Hypertensive Response to Exercise in Normotensive Men and Women with Abdominal Obesity: Association with Subclinical Adverse Cardiac Remodeling.Journal of clinical medicine · 2024Article
- Evaluation of Left Ventricular Systolic Functions of Patients with Exaggerated High Blood Pressure Response to Treadmill Exercise Test with Two-Dimensional Longitudinal Strain Imaging.Anatolian journal of cardiology · 2024Article
- Blood pressure behavior during exercise in patients with diastolic dysfunction and a hypertensive response to exercise.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Different levels of physical activity and risk of developing type 2 diabetes among adults with prediabetes: a population-based cohort study.Nutrition journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A hypertensive response to exercise (HRE) is frequently observed in individuals without hypertension or other cardiovascular disease. However, mechanisms and clinical implication of HRE is not fully elucidated. Endothelial dysfunction and increased stiffness of large artery contribute to development of HRE. From neurohormonal aspects, excess stimulation of sympathetic nervous system and augmented rise of angiotensin II seems to be important mechanism in HRE. Increasing evidences indicates that a HRE is associated with functional and structural abnormalities of left ventricle, especially when accompanied by increased central blood pressure. A HRE harbors prognostic significance in future development of hypertension and increased cardiovascular events, particularly if a HRE is documented in moderate intensity of exercise. As supported by previous studies, a HRE is not a benign phenomenon, however, currently, whether to treat a HRE is controversial with uncertain treatment strategy. Considering underlying mechanisms, angiotensin receptor blockers and beta blockers can be suggested in individuals with HRE, however, evidences for efficacy and outcomes of treatment of HRE in individuals without hypertension is scarce and therefore warrants further studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.