Evidence map›Paper›PMID 27468314›Full record

ArticleDiabetology & metabolic syndrome2016

Impact of metabolic syndrome on lipid target achievements in the Arabian Gulf: findings from the CEPHEUS study.

Ibrahim Al-Zakwani, Wael Al Mahmeed, Abdullah Shehab, Mohamed Arafah, Ali T Al-Hinai, Omer Al Tamimi, Mahmoud Al Awadhi, Shorook Al Herz, Faisal Al Anazi, Khalid Al Nemer and 14 more

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 16 institutions in 6 countries.

Ibrahim Al-ZakwaniDepartment of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman ; Gulf Health Research, Muscat, Oman.
Wael Al MahmeedHeart and Vascular Institute-Cleveland Clinic, Abu Dhabi, United Arab Emirates.
Abdullah ShehabUAE University, Alain, United Arab Emirates.
Mohamed ArafahKing Saud University Hospital, Riyadh, Kingdom of Saudi Arabia.
Ali T Al-HinaiMinistry of Health, Muscat, Oman.
Omer Al TamimiHamad Medical Corporation, Doha, Qatar.
Mahmoud Al AwadhiAl Amiri Hospital, Kuwait City, Kuwait.
Shorook Al HerzKing Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
Faisal Al AnaziMinistry of Health, Riyadh, Kingdom of Saudi Arabia.
Khalid Al NemerSchool of Medicine, Al-Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Kingdom of Saudi Arabia.
Othman MetwallyKing Fahad General Hospital, Jeddah, Kingdom of Saudi Arabia.
Akram AlkhadraKing Fahad Hospital of the University, Khobar, Kingdom of Saudi Arabia.
Mohammed FakhryKing Fahad Hospital of the University, Khobar, Kingdom of Saudi Arabia.
Hossam ElghetanySoliman Fakieh Hospital, Jeddah, Kingdom of Saudi Arabia.
Abdel Razak MedaniDubai Hospital, Dubai, United Arab Emirates.
Afzal Hussein YusufaliDubai Hospital, Dubai, United Arab Emirates.
Obaid Al JassimDubai Hospital, Dubai, United Arab Emirates.
Omar Al HallaqAmerican Hospital, Dubai, United Arab Emirates.
Fahad Omar Ahmed S BaslaibRashid Hospital, Dubai, United Arab Emirates.
Haitham AminBahrain Defense Force Hospital, Manama, Bahrain.
Khalid Al-WailiDepartment of Biochemistry, Sultan Qaboos University Hospital, P.O. Box 38, Al-Khod, 123 Muscat, Oman.
Khamis Al-HashmiDepartment of Physiology, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.
Raul D SantosLipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil.
Khalid Al-RasadiDepartment of Biochemistry, Sultan Qaboos University Hospital, P.O. Box 38, Al-Khod, 123 Muscat, Oman.
Dubai Hospital · AESultan Qaboos University · OMKing Fahd Hospital of the University · SAAmiri Hospital · KWHamad Medical Corporation · QAImam Mohammad ibn Saud Islamic University · SAKing Fahad Hospital Jeddah · SAKing Saud University · SAMinistry of Health · SAMinistry of Health · OMNational Guard Health Affairs · SARashid Hospital · AESoliman Fakeeh Hospital · SASultan Qaboos University Hospital · OMUnited Arab Emirates University · AEUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the impact of metabolic syndrome (MetS) on lipid target achievements in the Arabian Gulf.

methodsThe centralized pan-middle east survey on the undertreatment of hypercholesterolemia (CEPHEUS) included 4171 high and very high atherosclerotic cardiovascular disease (ASCVD) risk patients from six Arabian Gulf countries. Analyses were performed using univariate statistics.

resultsThe overall mean age was 57 ± 11 years, 41 % were females and 71 % had MetS. MetS patients were less likely to attain their HDL-C (34 vs. 79 %; P < 0.001), LDL-C (27 vs. 37 %; P < 0.001), non HDL-C (35 vs. 55 %; P < 0.001) and Apo B (35 vs. 54 %; P < 0.001) compared to those without MetS. Within the MetS cohort, those with very high ASCVD risk were less likely to attain their lipid targets compared to those with high ASCVD risk [HDL-C (32 vs. 41 %; P < 0.001), LDL-C (24 vs. 43 %; P < 0.001), non HDL-C (32 vs. 51 %; P < 0.001) and Apo B (33 vs. 40 %; P = 0.001)]. In those with MetS and very high ASCVD risk status, females were less likely to attain their HDL-C (27 vs. 36 %; P < 0.001), LDL-C (19 vs. 27 %; P < 0.001) and Apo B (30 vs. 35 %; P = 0.009) compared to males.

conclusionsMetS was associated with low lipid therapeutic targets. Women and those with very high ASCVD risk were also less likely to attain their lipid targets in the Arabian Gulf.

Indexed as

Arabian GulfBlood pressureCardiovascular diseasesHDL cholesterolLDL cholesterolMetabolic syndromeObesityTriglycerides

Identifiers

PMID27468314
PMCPMC4962507
OpenAlexW2476335417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.