ReviewFrontiers in plant science2016
Biosynthesis and Metabolic Fate of Phenylalanine in Conifers.
Review in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 166 citations in OpenAlex.
- Integrative systems biology analysis of barley transcriptome ─ hormonal signaling against biotic stress.PloS one · 2023Pooled it
- Phenylalanine coordinates antioxidant responses and ion homeostasis to enhance salinity tolerance in maize.Plant signaling & behavior · 2026Article
- Unveiling Dynamic Defense Pathways: Transcriptome Analysis of Phenylpropanoids and (Iso)flavonoids in Cowpea Leaves Post-CABMV Inoculation.Biochemical genetics · 2026Article
- Integrated metabolomics and transcriptomics reveal metabolite differences between wild and cultivated Angelica sinensis.BMC plant biology · 2026Article
- Oxford Nanopore Technologies Sequencing and Targeted Amino Acid Metabolomics Reveal Spatially Segregated Microbial Hijacking and Metabolic Collapse DuringFoods (Basel, Switzerland) · 2026Article
- Functional restructuring of the global soil microbiome under multiple stressors.Nature communications · 2026Article
- Unraveling the metabolic regulation of Eleutherococcus senticosus leaves by Penicillium oxalicum: insights from targeted and non-targeted metabolomics.BMC plant biology · 2026Article
- Changes in the expression of microRNAs regulate podophyllotoxin accumulation in Linum album cells to phenylalanine.BMC plant biology · 2026Article
- Organic fertilizer amendments reshape soil microbial communities and metabolic functions in sweet cherry production.Frontiers in plant science · 2026Article
- Integrated Transcriptomic and Metabolic Analyses Highlight Key Pathways Involved in the Somatic Embryogenesis ofPlants (Basel, Switzerland) · 2025Article
- Evolutionary Genomics Unravels the Responses and Adaptation to Climate Change in a Key Alpine Forest Tree Species.Molecular biology and evolution · 2025Article
- Metabolomic Insights into the Promotional Effect of Mulberry Leaf Flavonoids on Monascus Fermentation for the Production of Pigments.Applied biochemistry and biotechnology · 2025Article
- Nano-selenium mitigates arsenate toxicity in soybean roots by modulating phenylalanine and salicylic acid pathways.BMC plant biology · 2025Article
- Serum Metabolomic Profiling in Healthy Dogs Supplemented with Increasing Levels of Purified Beta-1,3/1,6-Glucans.Animals : an open access journal from MDPI · 2025Article
- Foliar Application of Amino Acids IncreasesPlants (Basel, Switzerland) · 2025Article
- Biological Processes Underlying Genetic Adaptation of Larches to Cold and Dry Winter Conditions in Eastern Siberia.Ecology and evolution · 2025Article
- Metabolomics and transcriptomics indicate the changes in medicinal components ofFrontiers in plant science · 2025Article
- Mitigating gadolinium toxicity in guar (Cyamopsis tetragonoloba L.) through the symbiotic associations with arbuscular mycorrhizal fungi: physiological and biochemical insights.BMC plant biology · 2024Article
- Nitrate Starvation Induces Lateral Root Organogenesis inInternational journal of molecular sciences · 2024Article
- Across-environment seed protein stability and genetic architecture of seed components in soybean.Scientific reports · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The amino acid phenylalanine (Phe) is a critical metabolic node that plays an essential role in the interconnection between primary and secondary metabolism in plants. Phe is used as a protein building block but it is also as a precursor for numerous plant compounds that are crucial for plant reproduction, growth, development, and defense against different types of stresses. The metabolism of Phe plays a central role in the channeling of carbon from photosynthesis to the biosynthesis of phenylpropanoids. The study of this metabolic pathway is particularly relevant in trees, which divert large amounts of carbon into the biosynthesis of Phe-derived compounds, particularly lignin, an important constituent of wood. The trunks of trees are metabolic sinks that consume a considerable percentage of carbon and energy from photosynthesis, and carbon is finally immobilized in wood. This paper reviews recent advances in the biosynthesis and metabolic utilization of Phe in conifer trees. Two alternative routes have been identified: the ancient phenylpyruvate pathway that is present in microorganisms, and the arogenate pathway that possibly evolved later during plant evolution. Additionally, an efficient nitrogen recycling mechanism is required to maintain sustained growth during xylem formation. The relevance of phenylalanine metabolic pathways in wood formation, the biotic interactions, and ultraviolet protection is discussed. The genetic manipulation and transcriptional regulation of the pathways are also outlined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.