Evidence map›Paper›PMID 27468189›Full record

ReviewWorld journal of gastroenterology2016

Selective intestinal decontamination for the prevention of early bacterial infections after liver transplantation.

Elena Resino, Rafael San-Juan, Jose Maria Aguado

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. Surgical Revision Promotes Presence of Enterococcus spp. in Abdominal Superficial Surgical Site Infections.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elena ResinoElena Resino, Rafael San-Juan, Jose Maria Aguado, Unit of Infectious Diseases, 12 de Octubre University Hospital, Madrid 28041, Spain.
Rafael San-JuanElena Resino, Rafael San-Juan, Jose Maria Aguado, Unit of Infectious Diseases, 12 de Octubre University Hospital, Madrid 28041, Spain.
Jose Maria AguadoElena Resino, Rafael San-Juan, Jose Maria Aguado, Unit of Infectious Diseases, 12 de Octubre University Hospital, Madrid 28041, Spain.
Research Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infection in the first month after liver transplantation is a frequent complication that poses a serious risk for liver transplant recipients as contributes substantially to increased length of hospitalization and hospital costs being a leading cause of death in this period. Most of these infections are caused by gram-negative bacilli, although gram-positive infections, especially Enterococcus sp. constitute an emerging infectious problem. This high rate of early postoperative infections after liver transplant has generated interest in exploring various prophylactic approaches to surmount this problem. One of these approaches is selective intestinal decontamination (SID). SID is a prophylactic strategy that consists of the administration of antimicrobials with limited anaerobicidal activity in order to reduce the burden of aerobic gram-negative bacteria and/or yeast in the intestinal tract and so prevent infections caused by these organisms. The majority of studies carried out to date have found SID to be effective in the reduction of gram-negative infection, but the effect on overall infection is limited due to a higher number of infection episodes by pathogenic enterococci and coagulase-negative staphylococci. However, difficulties in general extrapolation of the favorable results obtained in specific studies together with the potential risk of selection of multirresistant microorganisms has conditioned controversy about the routinely application of these strategies in liver transplant recipients.

Indexed as

Liver TransplantationAnti-Bacterial AgentsAntibiotic ProphylaxisDecontaminationGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsHumansIntestinesPostoperative ComplicationsAnti-Bacterial AgentsGram-negative bacterial infectionGram-positive bacterial infectionInfectionLiver transplantMultirresistantSelective intestinal decontamination

Identifiers

PMID27468189
PMCPMC4948279
OpenAlexW2489568229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.