ReviewWorld journal of gastroenterology2016
Is endoscopic papillary balloon dilatation really a risk factor for post-ERCP pancreatitis?
Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Comparative efficacy of balloon dilatation duration on patients with choledocholithiasis: a Bayesian network meta-analysis and systematic review.Surgical endoscopy · 2025Pooled it
- Morphology of the papilla can predict procedural safety and efficacy of ERCP-a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Efficacy and safety of three methods of endoscopic retrograde cholangiopancreatography in removing small common bile duct stones: a prospective multicenter randomized controlled study.Surgical endoscopy · 2025Trial
- Optimal dilation duration of 10 mm diameter balloons after limited endoscopic sphincterotomy for common bile duct stones: a randomized controlled trial.Scientific reports · 2024Trial
- Article
- Difficult biliary cannulation among patients with compensated liver cirrhosis: predictors and impact on complications.Scientific reports · 2026Article
- Safety and feasibility of omitting routine endoscopic nasobiliary drainage after ERCP for common bile duct stones: a prospective comparative study.BMC surgery · 2026Article
- Article
- Large balloon sphincteroplasty for CBD stone removal during acute cholangitis. Single center propensity-score matched cohort study.Surgical endoscopy · 2025Article
- Endoscopic retrograde cholangiopancreatography, endoscopic papillary balloon dilation, and laparoscopic hepatectomy for intra- and extrahepatic bile duct stones.World journal of gastrointestinal surgery · 2025Article
- Endoscopic nasobiliary drainage is superior to biliary stent placement in preventing postendoscopic papillary balloon dilation pancreatitis.Therapeutic advances in gastroenterology · 2025Article
- Case Series of Endoscopic Papillary Balloon Dilation for Children with Common Bile Duct Stones and a Review of the Literature.Journal of clinical medicine · 2024Article
- Endoscopic Management of Difficult Biliary Stones: An Evergreen Issue.Medicina (Kaunas, Lithuania) · 2024Review
- Efficacy and complications of inoperable malignant distal biliary obstruction treatment by metallic stents: fully covered or uncovered?Gastroenterology report · 2023Review
- Risk factors for ERCP-related complications and what is the specific role of ASGE grading system.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Single-operator peroral pancreatoscopy in the preoperative diagnostics of suspected main duct intraductal papillary mucinous neoplasms: efficacy and novel insights on complications.Surgical endoscopy · 2022Article
- Efficacy and safety of the rotatable sphincterotome during ERCP in patients with prior Billroth II gastrectomy (with videos).Surgical endoscopy · 2021Article
- Best Procedure for the Management of Common Bile Duct Stones via the Papilla: Literature Review and Analysis of Procedural Efficacy and Safety.Journal of clinical medicine · 2020Review
- Surgical procedure for unexpected balloon burst complication during endoscopic balloon dilatation in a patient with common bile duct stones.Surgical case reports · 2020Article
- Duodenal major papilla morphology can affect biliary cannulation and complications during ERCP, an observational study.BMC gastroenterology · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endoscopic papillary balloon dilatation (EPBD) is useful for decreasing early complications of endoscopic retrograde cholangio-pancreatography (ERCP), including bleeding, biliary infection, and perforation, but it is generally avoided in Western countries because of a relatively high reported incidence of post-ERCP pancreatitis (PEP). However, as the efficacy of endoscopic papillary large-balloon dilatation (EPLBD) becomes widely recognized, EPBD is attracting attention. Here we investigate whether EPBD is truly a risk factor for PEP, and seek safer and more effective EPBD procedures by reviewing past studies. We reviewed thirteen randomised control trials comparing EPBD and endoscopic sphincterotomy (EST) and ten studies comparing direct EPLBD and EST. Three randomized controlled trials of EPBD showed significantly higher incidence of PEP than EST, but no study of EPLBD did. Careful analysis of these studies suggested that longer and higher-pressure inflation of balloons might decrease PEP incidence. The paradoxical result that EPBD with small-calibre balloons increases PEP incidence while EPLBD does not may be due to insufficient papillary dilatation in the former. Insufficient dilatation could cause the high incidence of PEP through the use of mechanical lithotripsy and stress on the papilla at the time of stone removal. Sufficient dilation of the papilla may be useful in preventing PEP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.