Evidence map›Paper›PMID 27467920›Full record

ArticleOncoimmunology2016

Tumor evasion of humoral immunity mediated by proteolytic impairment of antibody triggered immune effector function.

Ningyan Zhang, Robert E Jordan, Zhiqiang An

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ningyan ZhangThe Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centerl at Houston , Hosuton, TX, USA.
Robert E JordanThe Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centerl at Houston , Hosuton, TX, USA.
Zhiqiang AnThe Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Centerl at Houston , Hosuton, TX, USA.
Brown Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune suppression is recognized as a hallmark of cancer and this notion is largely based on studies on cellular immunity. Our recent studies have demonstrated a potential new mechanism of cancer suppression of immunity by impairment of antibody effector function mediated by proteolytic enzymes in the tumor microenvironment.

Indexed as

Antibody immunitycancer immune evasionsingle proteolytic cleavage of the IgG hingetumor microenvironment

Identifiers

PMID27467920
PMCPMC4910702
OpenAlexW2415915337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.