ArticlePloS one2016
Interplay of Proximal Flow Confluence and Distal Flow Divergence in Patient-Specific Vertebrobasilar System.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Endovascular management of femoral artery duplication with a proposed anatomical classification.Surgical and radiologic anatomy : SRA · 2026Article
- Risk factors and predictive indicators of rupture in cerebral aneurysms.Frontiers in physiology · 2024Review
- Aortic hemodynamic and morphological analysis before and after repair of thoracoabdominal aortic aneurysm using a G-Branch endograft.Frontiers in physiology · 2023Article
- Influence of MRI-based boundary conditions on type B aortic dissection simulations in false lumen with or without abdominal aorta involvement.Frontiers in physiology · 2022Article
- A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile.Scientific reports · 2021Article
- Vertebral Artery Stenoses Contribute to the Development of Diffuse Plaques in the Basilar Artery.Frontiers in bioengineering and biotechnology · 2020Article
- Bifurcation Asymmetry of Small Coronary Arteries in Juvenile and Adult Mice.Frontiers in physiology · 2018Article
- Hepatic Hemangiomas Alter Morphometry and Impair Hemodynamics of the Abdominal Aorta and Primary Branches From Computer Simulations.Frontiers in physiology · 2018Article
- A comparison of postoperative morphometric and hemodynamic changes between saphenous vein and left internal mammary artery grafts.Physiological reports · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Approximately one-quarter of ischemic strokes involve the vertebrobasilar arterial system that includes the upstream flow confluence and downstream flow divergence. A patient-specific hemodynamic analysis is needed to understand the posterior circulation. The objective of this study is to determine the distribution of hemodynamic parameters in the vertebrobasilar system, based on computer tomography angiography images. Here, the interplay of upstream flow confluence and downstream flow divergence was hypothesized to be a determinant factor for the hemodynamic distribution in the vertebrobasilar system. A computational fluid dynamics model was used to compute the flow fields in patient-specific vertebrobasilar models (n = 6). The inlet and outlet boundary conditions were the aortic pressure waveform and flow resistances, respectively. A 50% reduction of total outlet area was found to induce a ten-fold increase in surface area ratio of low time-averaged wall shear stress (i.e., TAWSS ≤ 4 dynes/cm2). This study enhances our understanding of the posterior circulation associated with the incidence of atherosclerotic plaques.
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