ReviewNature methods2016
A practical guide to photoacoustic tomography in the life sciences.
Review in Nature methods, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 532 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
532 citing papers in PubMed.
- Integrating visual state space models with frequency selection for artifact reduction in photoacoustic tomography.Photoacoustics · 2026Article
- Blind single image restoration for ring-array photoacoustic tomography system via physics-aided unsupervised learning.Photoacoustics · 2026Article
- Photoacoustic and ultrasound Imaging of placental functions in gestational diabetes: From diagnosis to precision interventions.Photoacoustics · 2026Review
- Stochastic numerical head phantoms to enable virtual imaging studies of transcranial photoacoustic computed tomography.Photoacoustics · 2026Article
- A Model-Based Joint Feature Fusion framework for limited-view photoacoustic tomography reconstruction.Photoacoustics · 2026Article
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- Differential aperture modulation enables high-fidelity 3D photoacoustic imaging.Photoacoustics · 2026Article
- Robust automated three-dimensional speed-of-sound compensation for hemispherical photoacoustic computed tomography.Photoacoustics · 2026Article
- Lipid Bilayer-Confined J-Aggregation Transduces Cell Membrane Mechanics into Photoacoustic Signals.Journal of the American Chemical Society · 2026Article
- Mapping blood vessels and oxygenation throughout the whole mouse brain with dual-frequency fiber-array photoacoustic computed tomography.Light, science & applications · 2026Article
- Pigmentation-dependent skin injury thresholds with nanosecond single-pulse laser exposure.Journal of biomedical optics · 2026Article
- Can Photoacoustic Imaging Provide a Sensitive Marker for Early Detection of Diabetic Nephropathy.Journal of biophotonics · 2026Article
- 1064 nm-absorbing semiconducting polymer nanoparticles for multimodal photoacoustic and fluorescence imaging.Biomedical optics express · 2026Article
- PIT-Net: Physics-informed transformer with differentiable diffusion constraints for quantitative photoacoustic tomography of deep tissues.Photoacoustics · 2026Article
- Advances in Wearable Bioimaging.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Quantitative evaluation of key factors influencing hepatic oxygen saturation measurement by photoacoustic imaging in mice.Quantitative imaging in medicine and surgery · 2026Article
- Three-dimensional aperture-driven photoacoustic tomography (3D-ADPAT).Science advances · 2026Article
- Shape-optimized Model-based Reconstruction Algorithm for Radiacoustic Imaging.Applied physics letters · 2026Article
- Noninvasive whole-brain imaging of glymphatic dynamics.Science advances · 2026Article
- Investigating Age-Dependent Oxygenation and Blood Perfusion in a Mouse Model of Peripheral Artery Disease (PAD) Using Multispectral Optoacoustic Tomography (MSOT), Laser Speckle Contrast Imaging (LSCI) and Histology.Diagnostics (Basel, Switzerland) · 2026Article
472 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The life sciences can benefit greatly from imaging technologies that connect microscopic discoveries with macroscopic observations. One technology uniquely positioned to provide such benefits is photoacoustic tomography (PAT), a sensitive modality for imaging optical absorption contrast over a range of spatial scales at high speed. In PAT, endogenous contrast reveals a tissue's anatomical, functional, metabolic, and histologic properties, and exogenous contrast provides molecular and cellular specificity. The spatial scale of PAT covers organelles, cells, tissues, organs, and small animals. Consequently, PAT is complementary to other imaging modalities in contrast mechanism, penetration, spatial resolution, and temporal resolution. We review the fundamentals of PAT and provide practical guidelines for matching PAT systems with research needs. We also summarize the most promising biomedical applications of PAT, discuss related challenges, and envision PAT's potential to lead to further breakthroughs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.