Evidence map›Paper›PMID 27466318›Full record

ArticleMolecular biology of the cell2016

Sir protein-independent repair of dicentric chromosomes in Saccharomyces cerevisiae.

David F McCleary, David Lee Steakley, Jasper Rine

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David F McClearyDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
David Lee SteakleyDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
Jasper RineDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 jrine@berkeley.edu.
National Institutes of Health · US

Funding

GENETIC ANALYSIS OF THE GENES CONTROLLING A POSITIONR01GM031105 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI RINE, JASPER D · 1985 to 2020
$6.4M
GENETIC ANALYSIS OF GENES CONTROLLING A POSITION EFFECTR37GM031105 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI RINE, JASPER D · 1999 to 2008
$3.5M
Regulation of yeast chronological lifespan during growth in high calorie media.F31AG047795 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCCLEARY, DAVID F · 2014 to 2016
$108k
NIA NIH HHS F31 AG047795NIGMS NIH HHS R01 GM031105NIGMS NIH HHS R37 GM031105
6 · The paper itself

Abstract

Sir2 protein has been reported to be recruited to dicentric chromosomes under tension, and such chromosomes are reported to be especially vulnerable to breakage in sir2Δ mutants. We found that the loss of viability in such mutants was an indirect effect of the repression of nonhomologous end joining in Sir(-) mutants and that the apparent recruitment of Sir2 protein to chromosomes under tension was likely due to methodological weakness in early chromatin immunoprecipitation studies.

Indexed as

CentromereChromatinChromosomes, FungalDNA-Binding ProteinsDNA RepairGene Expression Regulation, FungalSaccharomyces cerevisiaeSilent Information Regulator Proteins, Saccharomyces cerevisiaeTelomereTranscription, GeneticChromatinDNA-Binding ProteinsSilent Information Regulator Proteins, Saccharomyces cerevisiae

Identifiers

PMID27466318
PMCPMC5025274
OpenAlexW2484883488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.