Evidence map›Paper›PMID 27466240›Full record

ArticleBMJ open2016

Association of dental and periodontal disease with chronic kidney disease in patients of a single, tertiary care centre in Thailand.

R Ausavarungnirun, S Wisetsin, N Rongkiettechakorn, S Chaichalermsak, U Udompol, M Rattanasompattikul

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  7. Impact of circadian clock protein Bmal1 on experimentally-induced periodontitis-associated renal injury.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

R AusavarungnirunMedicine Division, Medical Department, Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom, Thailand.
S WisetsinDepartment of Oral and Maxillofacial Radiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
N RongkiettechakornMedicine Division, Medical Department, Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom, Thailand.
S ChaichalermsakDepartment of Oral Medicine and Periodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
U UdompolMedicine Department, Saraburi Hospital, Muang, Saraburi, Thailand.
M RattanasompattikulMedicine Division, Medical Department, Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom, Thailand.
Mahidol University · THRatchaburi Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have shown an association between oral diseases and chronic kidney disease (CKD), and regular oral care may be an important strategy for reducing the burden of CKD. The objective of this study was therefore to evaluate the association between dental and periodontal diseases in Thai patients with various stages of CKD.

methodsThis was designed as a cross-sectional study and was performed between 2011 and 2012. The inclusion criteria were age >20 years and a diagnosis of CKD for at least 90 days. Data from medical records were collected, clinical oral examination was performed, and data were statistically analysed.

resultsA total of 129 patients with different stages of CKD were included. Ninety-eight (76%) were men. The age range was 30-86 years. The Decay, Missing and Filling Tooth Index and the number of missing teeth were higher in the group with moderate CKD than in the control group (21 vs 17.5, p=0.045, 13 vs 8 p=0.01, respectively). Serum albumin levels decreased when estimated glomerular filtration rate (eGFR) was in decline (γ=0.33; p=0.002). Severe periodontitis was significantly higher in the 'more severe CKD group' (eGFR <60 mL/min/1.73 m(2)) than in the 'less severe CKD group' (eGFR 60-90 mL/min/1.73 m(2); 24% vs 9%, p=0.03). Severe periodontitis, eGFR <30 mL/min/1.73 m(2) and brushing teeth more than once a day were associated with hypoalbuminaemia (defined as <3.8 g/dL) (OR (95% CI) 5.88 (1.64 to 21.11), 5.80 (1.58 to 21.35) and 0.16 (0.05 to 0.60), respectively).

conclusionsSevere periodontal diseases were more prevalent in patients with more severe CKD than in those with less severe CKD. The novel association of serum albumin levels with periodontal status was demonstrated in progressive stages of CKD. Dental intervention may be beneficial from the early stages of CKD.

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesCross-Sectional StudiesFemaleHumansHypoalbuminemiaMaleMiddle AgedPeriodontal DiseasesPrevalenceRenal Insufficiency, ChronicRisk FactorsSeverity of Illness IndexTertiary Care CentersChronic kidney diseaseComplications of chronic kidney diseaseDental diseaseHypoalbuminemiaPeriodontal disease

Identifiers

PMID27466240
PMCPMC4964184
OpenAlexW2497314523

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.