Evidence map›Paper›PMID 27465921›Full record

ArticlePublic health nutrition2017

Declines in traditional marine food intake and vitamin D levels from the 1960s to present in young Alaska Native women.

Diane M O'Brien, Kenneth E Thummel, Lisa R Bulkow, Zhican Wang, Brittany Corbin, Joseph Klejka, Scarlett E Hopkins, Bert B Boyer, Thomas W Hennessy, Rosalyn Singleton

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

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  5. Prenatal vitamin D levels and postpartum hemorrhage in a rural Alaska cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  17. One health in the circumpolar North.International journal of circumpolar health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Diane M O'Brien1Center for Alaska Native Health Research,Institute of Arctic Biology,University of Alaska,PO Box 757000,Fairbanks,AK 99775-7000,USA.
Kenneth E Thummel3School of Pharmacy,University of Washington,Seattle,WA,USA.
Lisa R Bulkow4Arctic Investigations Program,Division of Preparedness and Emerging Infections,National Center for Emerging and Zoonotic Infectious Diseases,Centers for Disease Control and Prevention,Anchorage,AK,USA.
Zhican Wang3School of Pharmacy,University of Washington,Seattle,WA,USA.
Brittany Corbin2Department of Biology and Wildlife,University of Alaska,Fairbanks,AK,USA.
Joseph Klejka5Yukon Kuskokwim Health Corporation,Bethel,AK,USA.
Scarlett E Hopkins1Center for Alaska Native Health Research,Institute of Arctic Biology,University of Alaska,PO Box 757000,Fairbanks,AK 99775-7000,USA.
Bert B Boyer1Center for Alaska Native Health Research,Institute of Arctic Biology,University of Alaska,PO Box 757000,Fairbanks,AK 99775-7000,USA.
Thomas W Hennessy4Arctic Investigations Program,Division of Preparedness and Emerging Infections,National Center for Emerging and Zoonotic Infectious Diseases,Centers for Disease Control and Prevention,Anchorage,AK,USA.
Rosalyn Singleton4Arctic Investigations Program,Division of Preparedness and Emerging Infections,National Center for Emerging and Zoonotic Infectious Diseases,Centers for Disease Control and Prevention,Anchorage,AK,USA.
University of Alaska Fairbanks · USUniversity of Washington · USAlaska Native Tribal Health Consortium · USCenters for Disease Control and Prevention · USNational Center for Emerging and Zoonotic Infectious Diseases · USNative Health · USYukon Kuskokwim Health Corporation · US

Funding

Pharmacogenetics in Rural and Underserved PopulationsU01GM092676 · NIGMS · UNIVERSITY OF WASHINGTON · PI BURKE, WYLIE G., THUMMEL, KENNETH E. · 2010 to 2014
$9.9M
Hormonal Regulation of Human CYP3AR01GM063666 · NIGMS · UNIVERSITY OF WASHINGTON · PI THUMMEL, KENNETH E. · 2002 to 2017
$5.3M
Pilot Project ProgramP30GM103325 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI O'BRIEN, DIANE MARIE · 2012 to 2016
$5.3M
NIGMS NIH HHS P30 GM103325NIGMS NIH HHS R01 GM063666NIGMS NIH HHS U01 GM092676
6 · The paper itself

Abstract

objectiveTo measure the trends in traditional marine food intake and serum vitamin D levels in Alaska Native women of childbearing age (20-29 years old) from the 1960s to the present.

designWe measured a biomarker of traditional food intake, the δ15N value, and vitamin D level, as 25-hydroxycholecalciferol (25(OH)D3) concentration, in 100 serum samples from 20-29-year-old women archived in the Alaska Area Specimen Bank, selecting twenty-five per decade from the 1960s to the 1990s. We compared these with measurements of red-blood-cell δ15N values and serum 25(OH)D3 concentrations from 20-29-year-old women from the same region collected during the 2000s and 2010s in a Center for Alaska Native Health Research study.

settingThe Yukon Kuskokwim Delta region of south-west Alaska. SUBJECTS: Alaska Native women (n 319) aged 20-29 years at the time of specimen collection.

resultsIntake of traditional marine foods, as measured by serum δ15N values, decreased significantly each decade from the 1960s through the 1990s, then remained constant from the 1990s through the present (F 5,306=77·4, P<0·0001). Serum vitamin D concentrations also decreased from the 1960s to the present (F 4,162=26·1, P<0·0001).

conclusionsConsumption of traditional marine foods by young Alaska Native women dropped significantly between the 1960s and the 1990s and was associated with a significant decline in serum vitamin D concentrations. Studies are needed to evaluate the promotion of traditional marine foods and routine vitamin D supplementation during pregnancy for this population.

Indexed as

AdultAlaskaAlaska NativesCross-Sectional StudiesDietFemaleHumansMaleSeafoodVitamin DYoung AdultVitamin D25-Hydroxycholecalciferol concentrationArctic healthCircumpolar healthNutrition transitionRicketsStable isotope ratiosδ15N value

Identifiers

PMID27465921
PMCPMC5274583
OpenAlexW2478711049

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.