ArticleImmunology and cell biology2017
Early CCR6 expression on B cells modulates germinal centre kinetics and efficient antibody responses.
Article in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 41 citations in OpenAlex.
- Trial
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- Biosafety assessment of engineered CCL20 locked dimers in vivo.Cell biology and toxicology · 2025Article
- Biomarker expression level changes within rectal gut-associated lymphoid tissues in spinal cord-injured rats.ImmunoHorizons · 2025Article
- Fc-enhanced anti-CCR6 antibody elicits robust therapeutic effects across multiple autoimmune diseases.Frontiers in immunology · 2025Article
- Atypical chemokine receptors in the immune system.Nature reviews. Immunology · 2024Review
- Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.Nature communications · 2024Article
- Distinct metabolic requirements regulate B cell activation and germinal center responses.Nature immunology · 2023Article
- Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.Nature communications · 2023Article
- Article
- Germinal Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research to Clinical Trials.Clinical reviews in allergy & immunology · 2022Review
- Single-cell transcriptomic atlas reveals distinct immunological responses between COVID-19 vaccine and natural SARS-CoV-2 infection.Journal of medical virology · 2022Article
- Article
- TFrontiers in immunology · 2022Article
- Cecal Patches Generate Abundant IgG2b-Bearing B Cells That Are Reactive to Commensal Microbiota.Journal of immunology research · 2022Article
- Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis.Communications biology · 2021Article
- Article
- Pregnancy-induced effects on memory B-cell development in multiple sclerosis.Scientific reports · 2021Article
- DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers.JCI insight · 2020Article
- B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging.The Journal of experimental medicine · 2019Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The CC-chemokine receptor 6 (CCR6) can be detected on naive and activated B cells. Counterintuitively, its absence accelerates the appearance of germinal centres (GCs) and increases the production of low-affinity antibodies. The detailed mechanism of CCR6 function during the humoral response has remained elusive, but previously we identified a distinct CCR6
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.