Evidence map›Paper›PMID 27465668›Full record

ArticleJournal of endocrinological investigation2016

The use of serum anti-Mullerian hormone (AMH) levels and antral follicle count (AFC) to predict the number of oocytes collected and availability of embryos for cryopreservation in IVF.

L Kotanidis, K Nikolettos, S Petousis, B Asimakopoulos, E Chatzimitrou, G Kolios, N Nikolettos

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Article in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

L KotanidisLaboratory of Reproductive Physiology - In Vitro Fertilization, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece. drkotanidis@gmail.com.
K NikolettosEmbryokosmogenesis IVF Unit, Alexandroupolis, Greece.
S Petousis3rd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloníki, Greece.
B AsimakopoulosLaboratory of Physiology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
E Chatzimitrou4th DYPE, Thessaloníki, Greece.
G KoliosLaboratory of Pharmacology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
N NikolettosLaboratory of Reproductive Physiology - In Vitro Fertilization, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Democritus University of Thrace · GRAristotle University of Thessaloniki · GRUniversity Hospital of Alexandroupolis · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the predictive value of anti-Mullerian hormone (AMH) and antral follicle count (AFC) on the final number of oocytes retrieved and the availability of embryos for cryopreservation in in vitro fertilization (IVF) cycles. PATIENTS AND

methodsIn this prospective study, one hundred and twenty women in their first IVF treatment were enrolled. The short stimulation agonist protocol was used for controlled ovarian hyperstimulation in all cases. Serum AMH levels were measured during the menstrual cycle preceding treatment. AFC was measured in cycle day 2, just before starting ovarian stimulation.

resultsA strong, positive correlation between AMH, AFC and the number of collected oocytes was found. The patients with available and suitable supplementary embryos for cryopreservation had higher levels of AMH and larger numbers of AFC.

conclusionAMH and AFC appear to be valuable markers mainly for ovarian reserve and response to IVF treatment. Serum AMH levels and AFC are significantly associated with the number of retrieved oocytes. Also, a positive correlation with the availability of supernumerary embryos suitable for cryopreservation was observed.

Indexed as

AdultAnti-Mullerian HormoneBiomarkersCryopreservationEmbryo, MammalianEmbryo TransferEnzyme-Linked Immunosorbent AssayFemaleFertilization in VitroFollicle Stimulating HormoneHumansOocytesOvarian FollicleProspective StudiesUltrasonographyYoung AdultAnti-Mullerian HormoneBiomarkersFollicle Stimulating HormoneAFCAMHCryopreservationEmbryosIVFOocytes

Identifiers

PMID27465668
OpenAlexW2498989616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.