Evidence map›Paper›PMID 27465385›Full record

ArticleForensic science, medicine, and pathology2016

Sudden unexpected death from an undiagnosed histiocytic sarcoma in an adolescent female.

H R Haynes, Z Melegh, S Vanjani, M Cieka, S Beavers, N Rooney, B Purdue

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Forensic science, medicine, and pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Sudden Unexpected Death Caused by Cardiac Metastasization from Histiocytic Sarcoma.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

H R HaynesLevel 1 Neuroscience, Learning and Research Building, University of Bristol, Bristol, BS10 5NB, UK. harryrhaynes@doctors.org.uk.
Z MeleghDepartment of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.
S VanjaniDepartment of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.
M CiekaDepartment of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.
S BeaversDepartment of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.
N RooneyDepartment of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.
B PurdueIndependent Forensic Pathologist, Dorset, UK.
North Bristol NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A previously well 15-year-old female who was awaiting medical investigations for a proptosed right eye collapsed and died suddenly while walking. Postmortem examination revealed diffuse distortion and infiltration of multiple organs by a suspected neoplastic process. Histology confirmed the invasion of multiple organs by atypical cells and myocardial infiltration was the likely cause of death. An extensive panel of immunohistochemistry established the diagnosis of a histiocytic sarcoma. Sudden unexpected death due to a clinically undiagnosed neoplasia in childhood and adolescence is uncommon. This is the first report of a histiocytic sarcoma causing sudden unexpected death and highlights the importance of considering undiagnosed hematological malignancies when examining a case of sudden death at postmortem.

Indexed as

AdolescentDeath, SuddenHistiocytic SarcomaHumansHypoxiaLungMaleMyocardiumHistiocytic sarcomaPostmortemSudden death

Identifiers

PMID27465385
OpenAlexW2502393637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.