Evidence map›Paper›PMID 27465282›Full record

Trial reportAIDS (London, England)2016

A pilot trial of pentoxifylline on endothelial function and inflammation in HIV-infected patients initiating antiretroviral therapy.

Samir K Gupta, Michael P Dubé, James H Stein, Matthias A Clauss, Ziyue Liu

Abstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in AIDS (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Epidemiology of ischemic heart disease in HIV.Current opinion in HIV and AIDS · 2017
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samir K GuptaaDivision of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Indiana bDivision of Infectious Diseases, University of Southern California Keck School of Medicine, Los Angeles, California cDivision of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin dDepartment of Cellular & Integrative Physiology, Center for Vascular Biology eDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Michael P Dubé
James H Stein
Matthias A Clauss
Ziyue Liu

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Indiana Clinical and Translational Science Institute (UL1)UL1TR000006 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2012 to 2013
$5.6M
HIV, Inflammation, and Endothelial DysfunctionR01HL095149 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI CLAUSS, MATTHIAS, GUPTA, SAMIR KUMAR · 2008 to 2012
$4.1M
EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT: NEUROLOGICAL DISORDERS:ALZ, PDC06RR020128 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FIFE, ROSE S · 2004 to 2004
$3.7M
OPTICAL TOMOGRAPHY TO MONITOR INTRATUMORAL BLOOD FLOWF32HL009526 · NHLBI · GEORGIA SOUTHERN UNIVERSITY · PI WANG, XIAO-JUN J · 1995 to 1997
–
NCATS NIH HHS UL1 TR000006NCATS NIH HHS UL1 TR001108NCRR NIH HHS C06 RR020128NHLBI NIH HHS F32 HL009526NHLBI NIH HHS R01 HL095149
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiretroviral Therapy, Highly ActiveAdultBiomarkersEndothelium, VascularFemaleHIV InfectionsHumansInflammationMalePentoxifyllinePilot ProjectsVasculitisVasodilationVasodilator AgentsBiomarkersPentoxifyllineVasodilator Agents

Identifiers

PMID27465282
PMCPMC4968583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.