Evidence map›Paper›PMID 27465246›Full record

ArticleBMC research notes2016

Neurosyphilis as a great imitator: a case report.

Liis Sabre, Mark Braschinsky, Pille Taba

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Neurosyphilis: A Monkey Among Men.Journal of community hospital internal medicine perspectives · 2022
    Article
  8. Article
  9. Article
  10. Observational
  11. Neurosyphilis, A True Chameleon of Neurology.Annals of Indian Academy of Neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Liis SabreDepartment of Neurology, Neurology Clinic, Tartu University Hospital, 8 L. Puusepa Street, 51014, Tartu, Estonia. liis.sabre@kliinikum.ee.
Mark BraschinskyDepartment of Neurology, Neurology Clinic, Tartu University Hospital, 8 L. Puusepa Street, 51014, Tartu, Estonia.
Pille TabaDepartment of Neurology, Neurology Clinic, Tartu University Hospital, 8 L. Puusepa Street, 51014, Tartu, Estonia.
Tartu University Hospital · EEUniversity of Tartu · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurosyphilis is defined as any involvement of the central nervous system by the bacterium Treponema pallidum. Movement disorders as manifestations of syphilis have been reported quite rarely. CASE PRESENTATION: We report a case of a 42-year-old Russian man living in Estonia with rapidly progressive dementia and movement disorders manifesting as myoclonus, cerebellar ataxia and parkinsonism. The mini mental state examination score was 12/30. After excluding different neurodegenerative causes, further diagnostic testing was consistent with neurosyphilis. Treatment with penicillin was started and 6 months later his mini mental state examination score was 25/30 and he had no myoclonus, parkinsonism or cerebellar dysfunction.

conclusionSince syphilis is easily diagnosed and treatable, it should be considered and tested in patients with cognitive impairment and movement disorders.

Indexed as

AdultAnti-Bacterial AgentsDiagnosis, DifferentialHumansMaleMyoclonic Cerebellar DyssynergiaNeurosyphilisParkinsonian DisordersPenicillinsTreatment OutcomeTreponema pallidumAnti-Bacterial AgentsPenicillinsDementiaMovement disordersNeurosyphilis

Identifiers

PMID27465246
PMCPMC4964046
OpenAlexW2500516664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.