Evidence map›Paper›PMID 27463666›Full record

ArticleScience (New York, N.Y.)2016

Response to Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme".

Shinya Watanabe, Craig L Peterson

Abstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Multicolor single-molecule FRET for DNA and RNA processes.Current opinion in structural biology · 2021
    Review
  4. Review
  5. Review
  6. Review
  7. Roles of the INO80 and SWR1 Chromatin Remodeling Complexes in Plants.International journal of molecular sciences · 2019
    Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Shinya WatanabeProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Craig L PetersonProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. craig.peterson@umassmed.edu.

Funding

Regulation of chromatin dynamicsR35GM122519 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Craig L Peterson · 2017 to 2026
$9.2M
Analysis of the yeast SWI1, SWI2, and SWI3 proteinsR37GM049650 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PETERSON, CRAIG L · 2006 to 2015
$4.9M
NIGMS NIH HHS R35 GM122519NIGMS NIH HHS R37 GM049650NIGMS NIH HHS R37-GM049650
6 · The paper itself

Abstract

Wang et al report a failure to reproduce our biochemical observation that the INO80C and SWR1C/SWR1/SWR-C chromatin remodeling enzymes catalyze replacement of nucleosomal H2A.Z with H2A when the substrate contains H3-K56Q. They point to technical problems with our dimer exchange assay. In response, we have recapitulated our findings using a mobility shift assay that was developed and employed by Wang and colleagues.

Indexed as

Chromatin Assembly and DisassemblyAdenosine TriphosphatasesHistonesMultienzyme ComplexesNucleosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdenosine TriphosphatasesHistonesMultienzyme ComplexesNucleosomesSaccharomyces cerevisiae Proteins

Identifiers

PMID27463666
PMCPMC8121161

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.