ArticlePloS one2016
Independent Associations between Sedentary Time, Moderate-To-Vigorous Physical Activity, Cardiorespiratory Fitness and Cardio-Metabolic Health: A Cross-Sectional Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The Effect of Exercise on Cardiometabolic Risk Factors in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- Objectively Measured Sedentary Behavior and Physical Fitness in Adults: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- The Association of Cardiorespiratory Fitness on Memory Function: Systematic Review.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Cardiorespiratory fitness and submaximal exercise dynamics in normal-weight obesity and metabolically healthy obesity.European journal of applied physiology · 2024Trial
- Two Family Gradients in Children's Physical Activity and Fitness: Socioeconomic Position, Family Structure, and Where They Diverge.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Fitness-related physical activity intensity explains most of the association between accelerometer data and cardiometabolic health in persons 50-64 years old.British journal of sports medicine · 2024Article
- Effects of Pilates Training on Cardiorespiratory Functions in Medical Conditions - Comprehensive Approach: A Narrative Review.Aging and disease · 2024Review
- Determinants of multimorbidity in older adults in Iran: a cross-sectional study using latent class analysis on the Bushehr Elderly Health (BEH) program.BMC geriatrics · 2024Article
- The association between moderate-to-vigorous physical activity and health-related quality of life in Chinese adolescents: the mediating roles of emotional intelligence and perceived stress.Frontiers in psychology · 2024Article
- Associations of objectively measured physical activity, sedentary time and cardiorespiratory fitness with adipose tissue insulin resistance and ectopic fat.International journal of obesity (2005) · 2023Article
- Mediator Effect of Cardiorespiratory Fitness on the Association between Physical Activity and Lung Function in Adults: Cross-Sectional Results from the Epimov Study.International journal of environmental research and public health · 2022Article
- Objectively Measured Physical Activity Is Associated With Body Composition and Metabolic Profiles of Pacific and New Zealand European Women With Different Metabolic Disease Risks.Frontiers in physiology · 2021Article
- Differential associations of engagement in physical activity and estimated cardiorespiratory fitness with brain volume in middle-aged to older adults.Brain imaging and behavior · 2020Article
- Relationship between sleep duration and TV time with cardiometabolic risk in adolescents.Environmental health and preventive medicine · 2020Article
- Impact of unhealthy lifestyle on cardiorespiratory fitness and heart rate recovery of medical science students.BMC public health · 2020Article
- Physical Activity and Sedentary Time: Association with Metabolic Health and Liver Fat.Medicine and science in sports and exercise · 2019Article
- Biomarkers of cardiometabolic health are associated with body composition characteristics but not physical activity in persons with spinal cord injury.The journal of spinal cord medicine · 2019Article
- Association of objectively measured sedentary behavior and physical activity with cardiometabolic risk markers in older adults.PloS one · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to study the independent associations of sedentary time (ST), moderate-to-vigorous physical activity (MVPA), and objectively measured cardiorespiratory fitness (CRF) with clustered cardio-metabolic risk and its individual components (waist circumference, fasting glucose, HDL-cholesterol, triglycerides and blood pressure). We also investigated whether any associations between MVPA or ST and clustered cardio-metabolic risk were mediated by CRF. MVPA, ST, CRF and individual cardio-metabolic components were measured in a population-based sample of 341 adults (age 53.8 ± 8.9 years; 61% men) between 2012 and 2014. MVPA and ST were measured with the SenseWear pro 3 Armband and CRF was measured with a maximal exercise test. Multiple linear regression models and the product of coefficients method were used to examine independent associations and mediation effects, respectively. Results showed that low MVPA and low CRF were associated with a higher clustered cardio-metabolic risk (β = -0.26 and β = -0.43, both p<0.001, respectively). CRF explained 73% of the variance in the association between MVPA and clustered cardio-metabolic risk and attenuated this association to non-significance. After mutual adjustment for MVPA and ST, CRF was the most important risk factor for a higher clustered cardio-metabolic risk (β = -0.39, p<0.001). In conclusion, because of the mediating role of CRF, lifestyle-interventions need to be feasible yet challenging enough to lead to increases in CRF to improve someone's cardio-metabolic health.
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