ArticleCell discovery2016
Cellular mechanisms for cargo delivery and polarity maintenance at different polar domains in plant cells.
Article in Cell discovery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Memory in the wall: expanding our understanding of the roles of plant cell walls.The New phytologist · 2026Review
- Biosynthesis of very Long-chain fatty acids is required for Arabidopsis auxin-mediated embryonic and post-embryonic development.The Plant journal : for cell and molecular biology · 2025Article
- Over 25 years of decrypting PIN-mediated plant development.Nature communications · 2024Review
- Guidelines for naming and studying plasma membrane domains in plants.Nature plants · 2024Review
- Arabidopsis flippase ALA3 is required for adjustment of early subcellular trafficking in plant response to osmotic stress.Journal of experimental botany · 2023Article
- Polar localization of a rice silicon transporter requires isoleucine at both C- and N-termini as well as positively charged residues.The Plant cell · 2023Article
- Pole position: How plant cells polarize along the axes.The Plant cell · 2022Review
- Characterization and expression profiling of PIN auxin efflux transporters reveal their role in developmental and abiotic stress conditions in rice.Frontiers in plant science · 2022Article
- Local endocytosis of sucrose transporter 2 in duckweed reveals the role of sucrose transporter 2 in guard cells.Frontiers in plant science · 2022Article
- Calcium-dependent protein kinase 29 modulates PIN-FORMED polarity and Arabidopsis development via its own phosphorylation code.The Plant cell · 2021Article
- Correlative Light-Environmental Scanning Electron Microscopy of Plasma Membrane Efflux Carriers of Plant Hormone Auxin.Biomolecules · 2021Article
- Of Cells, Strands, and Networks: Auxin and the Patterned Formation of the Vascular System.Cold Spring Harbor perspectives in biology · 2021Review
- AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells.Current biology : CB · 2021Article
- Quantitative and dynamic cell polarity tracking in plant cells.The New phytologist · 2021Article
- Modulation of plant root growth by nitrogen source-defined regulation of polar auxin transport.The EMBO journal · 2021Article
- Role ofPlant direct · 2020Article
- Directional auxin fluxes in plants by intramolecular domain-domain coevolution of PIN auxin transporters.The New phytologist · 2020Article
- TRIPP Is a Plant-Specific Component of the Arabidopsis TRAPPII Membrane Trafficking Complex with Important Roles in Plant Development.The Plant cell · 2020Article
- Arabidopsis Flippases Cooperate with ARF GTPase Exchange Factors to Regulate the Trafficking and Polarity of PIN Auxin Transporters.The Plant cell · 2020Article
- SNARE Complexity in Arbuscular Mycorrhizal Symbiosis.Frontiers in plant science · 2020Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The asymmetric localization of proteins in the plasma membrane domains of eukaryotic cells is a fundamental manifestation of cell polarity that is central to multicellular organization and developmental patterning. In plants, the mechanisms underlying the polar localization of cargo proteins are still largely unknown and appear to be fundamentally distinct from those operating in mammals. Here, we present a systematic, quantitative comparative analysis of the polar delivery and subcellular localization of proteins that characterize distinct polar plasma membrane domains in plant cells. The combination of microscopic analyses and computational modeling revealed a mechanistic framework common to diverse polar cargos and underlying the establishment and maintenance of apical, basal, and lateral polar domains in plant cells. This mechanism depends on the polar secretion, constitutive endocytic recycling, and restricted lateral diffusion of cargos within the plasma membrane. Moreover, our observations suggest that polar cargo distribution involves the individual protein potential to form clusters within the plasma membrane and interact with the extracellular matrix. Our observations provide insights into the shared cellular mechanisms of polar cargo delivery and polarity maintenance in plant cells.
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