ArticleCell discovery2016
PBR1 selectively controls biogenesis of photosynthetic complexes by modulating translation of the large chloroplast gene Ycf1 in Arabidopsis.
Article in Cell discovery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 30 citations in OpenAlex.
- Editing and synthetic engineering of chloroplast genomes.Plant communications · 2026Review
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- Comprehensive analysis of complete Chloroplast genome sequence of Cardiospermum halicacabum L. (Sapindaceae).Scientific reports · 2025Article
- Comparative and evolutionary analysis of chloroplast genomes from five rare Styrax species.BMC genomics · 2025Article
- Comparative Analysis of the Chloroplast Genomes of theInternational journal of molecular sciences · 2024Article
- The complete chloroplast genomes and comparative study of the two tung trees of Vernicia (Euphorbiaceae).BMC genomics · 2024Article
- Analysis of chloroplast genome structure and phylogeny of the traditional medicinal of Ardisia crispa (Myrsinaceae).Scientific reports · 2024Article
- Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants.FEBS open bio · 2024Article
- Chloroplast genomes in sevenFrontiers in genetics · 2024Article
- More than a spiny morphology: plastome variation in the prickly pear cacti (Opuntieae).Annals of botany · 2023Article
- Chloroplast protein import machinery and quality control.The FEBS journal · 2022Review
- Revised Species Delimitation in the Giant Water Lily GenusFrontiers in plant science · 2022Article
- Exploring the evolutionary characteristics between cultivated tea and its wild relatives using complete chloroplast genomes.BMC ecology and evolution · 2021Article
- Protein import into chloroplasts and its regulation by the ubiquitin-proteasome system.Biochemical Society transactions · 2020Review
- An RNA Chaperone-Like Protein Plays Critical Roles in Chloroplast mRNA Stability and Translation in Arabidopsis and Maize.The Plant cell · 2019Article
- Feeding the world: improving photosynthetic efficiency for sustainable crop production.Journal of experimental botany · 2019Review
- Article
- Overexpression of the RieskeFeS Protein Increases Electron Transport Rates and Biomass Yield.Plant physiology · 2017Article
- An rbcL mRNA-binding protein is associated with C3 to C4 evolution and light-induced production of Rubisco in Flaveria.Journal of experimental botany · 2017Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biogenesis of photosystem I (PSI), cytochrome b 6 f (Cytb 6 f) and NADH dehydrogenase (NDH) complexes relies on the spatially and temporally coordinated expression and translation of both nuclear and chloroplast genes. Here we report the identification of photosystem biogenesis regulator 1 (PBR1), a nuclear-encoded chloroplast RNA-binding protein that regulates the concerted biogenesis of NDH, PSI and Cytb 6 f complexes. We identified Ycf1, one of the two largest chloroplast genome-encoded open reading frames as the direct downstream target protein of PBR1. Biochemical and molecular analyses reveal that PBR1 regulates Ycf1 translation by directly binding to its mRNA. Surprisingly, we further demonstrate that relocation of the chloroplast gene Ycf1 fused with a plastid-transit sequence to the nucleus bypasses the requirement of PBR1 for Ycf1 translation, which sufficiently complements the defects in biogenesis of NDH, PSI and Cytb 6 f complexes in PBR1-deficient plants. Remarkably, the nuclear-encoded PBR1 tightly controls the expression of the chloroplast gene Ycf1 at the translational level, which is sufficient to sustain the coordinated biogenesis of NDH, PSI and Cytb 6 f complexes as a whole. Our findings provide deep insights into better understanding of how a predominant nuclear-encoded factor can act as a migratory mediator and undergoes selective translational regulation of the target plastid gene in controlling biogenesis of photosynthetic complexes.
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