ArticleBiomicrofluidics2016
Fifty years of dielectrophoretic cell separation technology.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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Who cites it
29 citing papers in PubMed.
- 3D-Printed Closed-Channel Spiral Inertial Microfluidic Device for Size-Based Particle Separation.Micromachines · 2026Article
- Design and Performance Analysis of Spiral Microchannels for Efficient Particle Separation Using Inertial Microfluidics.Micromachines · 2025Article
- Quantifying the Electrophysiological Properties of Cells Using Dielectrophoresis.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Biomechanics of circulating cellular and subcellular bioparticles: beyond separation.Cell communication and signaling : CCS · 2024Review
- Article
- A Novel Microfluidic Dielectrophoresis Technology to Enable Rapid Diagnosis of Mycobacteria tuberculosis in Clinical Samples.The Journal of molecular diagnostics : JMD · 2023Article
- Fabrication of a new all-in-one microfluidic dielectrophoresis integrated chip and living cell separation.iScience · 2022Article
- Separation of Heterotrophic MicroalgaeFrontiers in bioengineering and biotechnology · 2022Article
- Modeling Brownian Microparticle Trajectories in Lab-on-a-Chip Devices with Time Varying Dielectrophoretic or Optical Forces.Micromachines · 2021Article
- Dielectrophoresis as a Tool to Reveal the Potential Role of Ion Channels and Early Electrophysiological Changes in Osteoarthritis.Micromachines · 2021Article
- Dielectrophoresis: Developments and applications from 2010 to 2020.Electrophoresis · 2021Review
- A Prominent Cell Manipulation Technique in BioMEMS: Dielectrophoresis.Micromachines · 2020Review
- Enrichment of bovine X-sperm using microfluidic dielectrophoretic chip: A proof-of- concept study.Heliyon · 2020Article
- Biosensors Based on Mechanical and Electrical Detection Techniques.Sensors (Basel, Switzerland) · 2020Review
- AC electrokinetic immobilization of organic dye molecules.Analytical and bioanalytical chemistry · 2020Article
- Separation, Characterization, and Handling of Microalgae by Dielectrophoresis.Microorganisms · 2020Review
- High-Sensitivity in Dielectrophoresis Separations.Micromachines · 2020Review
- Manipulation and Localized Deposition of Particle Groups with Modulated Electric Fields.Micromachines · 2020Article
- Polarizability-Dependent Sorting of Microparticles Using Continuous-Flow Dielectrophoretic Chromatography with a Frequency Modulation Method.Micromachines · 2019Article
- Shaping and transporting diamagnetic sessile drops.Biomicrofluidics · 2019Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 1966, Pohl and Hawk [Science 152, 647-649 (1966)] published the first demonstration of dielectrophoresis of living and dead yeast cells; their paper described how the different ways in which the cells responded to an applied nonuniform electric field could form the basis of a cell separation method. Fifty years later, the field of dielectrophoretic (DEP) cell separation has expanded, with myriad demonstrations of its ability to sort cells on the basis of differences in electrical properties without the need for chemical labelling. As DEP separation enters its second half-century, new approaches are being found to move the technique from laboratory prototypes to functional commercial devices; to gain widespread acceptance beyond the DEP community, it will be necessary to develop ways of separating cells with throughputs, purities, and cell recovery comparable to gold-standard techniques in life sciences, such as fluorescence- and magnetically activated cell sorting. In this paper, the history of DEP separation is charted, from a description of the work leading up to the first paper, to the current dual approaches of electrode-based and electrodeless DEP separation, and the path to future acceptance outside the DEP mainstream is considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.