ReviewFrontiers in plant science2016
Multi-Substrate Terpene Synthases: Their Occurrence and Physiological Significance.
Review in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
78 citing papers in PubMed, 176 citations in OpenAlex.
- Expansion and functional diversification of terpene synthases shape volatile terpenoid landscape inActa pharmaceutica Sinica. B · 2026Article
- The Mevalonate Pathway: Innovations, Applications, and Challenges in Biotechnology with Emphasis on Fungal Biology.Journal of fungi (Basel, Switzerland) · 2026Review
- Genetic blueprint of herbaceous peony floral scent: evidence from terpene synthase, Nudix hydrolase, and prenyltransferase.Horticulture research · 2026Article
- Integrated Transcriptomic and Metabolomic Analyses Reveal the Mechanism by Which 5-Methoxyindole Enhances Sesquiterpenoids Production inPlants (Basel, Switzerland) · 2026Article
- Plant Terpenoids in Cardioprotection: An Overview of Their Therapeutic Potential.Current issues in molecular biology · 2026Review
- Resin-based response of Pinus pinaster and P. radiata during infection by Fusarium circinatum.Journal of experimental botany · 2026Article
- Mowing Enhances Insect Resistance inInsects · 2026Article
- Insights into dill (Anethum graveolens) flavor formation via integrative analysis of chromosomal-scale genome, metabolome and transcriptome.Journal of advanced research · 2026Article
- Integrated metabolomic and transcriptomic profiling uncovers a citrus terpene synthase withFrontiers in plant science · 2026Article
- Droplet based microfluidic and miniaturization at high-throughput level to screening heterologous secondary metabolites in microbes: A critical review.Biotechnology letters · 2025Review
- Isolation and Characterization of Two Monoterpene Synthases and a Sesquiterpene Synthase fromMetabolites · 2025Article
- Inhibitor treatment and subcellular localization analysis reveal the contribution of a cytosolic terpene synthase to the substantial release of anti-insect monoterpenes by Sphagneticola trilobata (L.) Pruski.Journal of advanced research · 2025Article
- Article
- Protein Prenylation in Plants: Mechanisms and Functional Implications.Plants (Basel, Switzerland) · 2025Review
- Transcriptomic and metabolomic study of the biosynthetic pathways of bioactive components in Amomum tsaoko fruits.BMC plant biology · 2025Article
- Untargeted metabolomics ofHeliyon · 2025Article
- Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Gene Expression Divergence inPlants (Basel, Switzerland) · 2024Article
- Isolation and characterisation of sesquiterpene synthase from aromatic orchid Phalaenopsis bellina (Rchb.f.) Christenson.Molecular biology reports · 2024Article
- The microbial biosynthesis of noncanonical terpenoids.Applied microbiology and biotechnology · 2024Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Terpene synthases are responsible for synthesis of a large number of terpenes in plants using substrates provided by two distinct metabolic pathways, the mevalonate-dependent pathway that is located in cytosol and has been suggested to be responsible for synthesis of sesquiterpenes (C15), and 2-C-methyl-D-erythritol-4-phosphate pathway located in plastids and suggested to be responsible for the synthesis of hemi- (C5), mono- (C10), and diterpenes (C20). Recent advances in characterization of genes and enzymes responsible for substrate and end product biosynthesis as well as efforts in metabolic engineering have demonstrated existence of a number of multi-substrate terpene synthases. This review summarizes the progress in the characterization of such multi-substrate terpene synthases and suggests that the presence of multi-substrate use might have been significantly underestimated. Multi-substrate use could lead to important changes in terpene product profiles upon substrate profile changes under perturbation of metabolism in stressed plants as well as under certain developmental stages. We therefore argue that multi-substrate use can be significant under physiological conditions and can result in complicate modifications in terpene profiles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.