ArticleFrontiers in plant science2016
Shotgun Label-free Proteomic Analysis of Clubroot (Plasmodiophora brassicae) Resistance Conferred by the Gene Rcr1 in Brassica rapa.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Advanced breeding techniques inPlant signaling & behavior · 2026Review
- Proteomics Integrated with Transcriptomics of Clubroot Resistant and SusceptibleInternational journal of molecular sciences · 2025Article
- Metabolomic Profiling Identifies Key Metabolites and Defense Pathways inInternational journal of molecular sciences · 2025Article
- Rapid introgression of the clubroot resistance geneMolecular breeding : new strategies in plant improvement · 2025Article
- Pre-soil fumigation with ammonium bicarbonate and lime modulates the rhizosphere microbiome to mitigate clubroot disease in Chinese cabbage.Frontiers in microbiology · 2024Article
- Lignin accumulation in cell wall plays a role in clubroot resistance.Frontiers in plant science · 2024Article
- Multi-Omics Approaches to Improve Clubroot Resistance in Brassica with a Special Focus onInternational journal of molecular sciences · 2022Review
- What Can We Learn from -Omics Approaches to Understand Clubroot Disease?International journal of molecular sciences · 2022Review
- Metabonomic profiling of clubroot-susceptible and clubroot-resistant radish and the assessment of disease-resistant metabolites.Frontiers in plant science · 2022Article
- A Proteome-Level Investigation IntoFrontiers in plant science · 2022Article
- Local Duplication of TIR-NBS-LRR Gene Marks Clubroot Resistance inFrontiers in plant science · 2021Article
- Comparative Transcriptome Analysis of Rutabaga (International journal of molecular sciences · 2020Article
- Understanding Host-Pathogen Interactions inPlants (Basel, Switzerland) · 2020Review
- iTRAQ-based quantitative analysis reveals proteomic changes in Chinese cabbage (Brassica rapa L.) in response to Plasmodiophora brassicae infection.Scientific reports · 2019Article
- Transcriptomic response in symptomless roots of clubroot infected kohlrabi (Brassica oleracea var. gongylodes) mirrors resistant plants.BMC plant biology · 2019Article
- Not in your usual Top 10: protists that infect plants and algae.Molecular plant pathology · 2018Review
- Transcriptome analysis of response to Plasmodiophora brassicae infection in the Arabidopsis shoot and root.BMC genomics · 2018Article
- HSP70 as a Mediator of Host-Pathogen Interaction in Arabidopsis thaliana During Plasmodiophora brassicae Infection.Physiologia plantarumArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clubroot, caused by the plasmodiophorid pathogen Plasmodiophora brassicae, is one of the most serious diseases on Brassica crops worldwide and a major threat to canola production in western Canada. Host resistance is the key strategy for clubroot management on canola. Several clubroot resistance (CR) genes have been identified, but the mechanisms associated with these CR genes are poorly understood. In the current study, a label-free shotgun proteomic approach was used to profile and compare the proteomes of Brassica rapa carrying and not carrying the CR gene Rcr1 in response to P. brassicae infection. A total of 527 differentially accumulated proteins (DAPs) were identified between the resistant (with Rcr1) and susceptible (without Rcr1) samples, and functional annotation of these DAPs indicates that the perception of P. brassicae and activation of defense responses are triggered via an unique signaling pathway distinct from common modes of recognition receptors reported with many other plant-pathogen interactions; this pathway appears to act in a calcium-independent manner through a not-well-defined cascade of mitogen-activated protein kinases and may require the ubiquitin-26S proteasome found to be related to abiotic stresses, especially the cold-stress tolerance in other studies. Both up-regulation of defense-related and down-regulation of pathogenicity-related metabolism was observed in plants carrying Rcr1, and these functions may all contribute to the CR mediated by Rcr1. These results, combined with those of transcriptomic analysis reported earlier, improved our understanding of molecular mechanisms associated with Rcr1 and CR at large, and identified candidate metabolites or pathways related to specific resistance mechanisms. Deploying CR genes with different modes of action may help improve the durability of CR.
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