ArticleFrontiers in microbiology2016
Endozoicomonas Are Specific, Facultative Symbionts of Sea Squirts.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Microbial Communities Vary by Body Region but Remain Consistent Across Color Morphs in the Solitary AscidianInternational journal of microbiology · 2026Article
- Subcuticular symbionts of intertidal brittle stars: diversity, host specificity, and functional potential.ISME communications · 2026Article
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- Biodiversity and Biological Interactions of Actinobacteria Associated with Deep Sea and Intertidal Marine Invertebrates.Marine drugs · 2025Article
- Generating gnotobiotic bivalves: a new method on Manila clam (Microbiology spectrum · 2025Article
- A genomic view of the bacterial family Endozoicomonadaceae in marine symbioses.Communications biology · 2025Review
- Epibiotic Bacteria Isolated from the Non-Indigenous SpeciesMicroorganisms · 2024Article
- Vanadium Accumulation and Reduction by Vanadium-Accumulating Bacteria Isolated from the Intestinal Contents of Ciona robusta.Marine biotechnology (New York, N.Y.) · 2024Article
- Effects of color variation and physiological state on ascidian microbiomes.MicrobiologyOpen · 2024Article
- Distinct microbial communities in an ascidian-crustacean symbiosis.Environmental microbiology reports · 2024Article
- Article
- Contrasting Marine Microbial Communities of the Fram Strait with the First Confirmed Record of CyanobacteriaBiology · 2023Article
- Colocalization and potential interactions ofScience advances · 2023Article
- Physiological changes during torpor favor association withFrontiers in microbiology · 2023Article
- Coral holobiont cues prime Endozoicomonas for a symbiotic lifestyle.The ISME journal · 2022Article
- High-resolution spatial and genomic characterization of coral-associated microbial aggregates in the coralScience advances · 2022Article
- Microbial diversity in tropical marine sediments assessed using culture-dependent and culture-independent techniques.Environmental microbiology · 2021Article
- Symbiotic Associations in Ascidians: Relevance for Functional Innovation and Bioactive Potential.Marine drugs · 2021Review
- The Ascidian-Derived Metabolites with Antimicrobial Properties.Antibiotics (Basel, Switzerland) · 2020Review
- Uncovering the Core Microbiome and Distribution of Palmerolide inMarine drugs · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ascidians are marine filter feeders and harbor diverse microbiota that can exhibit a high degree of host-specificity. Pharyngeal samples of Scandinavian and Mediterranean ascidians were screened for consistently associated bacteria by culture-dependent and -independent approaches. Representatives of the Endozoicomonas (Gammaproteobacteria, Hahellaceae) clade were detected in the ascidian species Ascidiella aspersa, Ascidiella scabra, Botryllus schlosseri, Ciona intestinalis, Styela clava, and multiple Ascidia/Ascidiella spp. In total, Endozoicomonas was detected in more than half of all specimens screened, and in 25-100% of the specimens for each species. The retrieved Endozoicomonas 16S rRNA gene sequences formed an ascidian-specific subclade, whose members were detected by fluorescence in situ hybridization (FISH) as extracellular microcolonies in the pharynx. Two strains of the ascidian-specific Endozoicomonas subclade were isolated in pure culture and characterized. Both strains are chemoorganoheterotrophs and grow on mucin (a mucus glycoprotein). The strains tested negative for cytotoxic or antibacterial activity. Based on these observations, we propose ascidian-associated Endozoicomonas to be commensals, living off the mucus continuously secreted into the pharynx. Members of the ascidian-specific Endozoicomonas subclade were also detected in seawater from the Scandinavian sampling site, which suggests acquisition of the symbionts by horizontal transmission. The combined results indicate a host-specific, yet facultative symbiosis between ascidians and Endozoicomonas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.