ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017
MRI of cerebral micro-vascular flow patterns: A multi-direction diffusion-weighted ASL approach.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Diffusion-weighted arterial spin labeling MRI to investigate mannitol-induced blood brain barrier disruption.Magnetic resonance imaging · 2025Article
- Analysis of dynamic contrast-enhanced T1-weighted imaging parameters in type II TIC breast lesions.Frontiers in oncology · 2025Article
- Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis.Scientific reports · 2023Article
- Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies.Fluids and barriers of the CNS · 2022Review
- Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Recent Advances in Parameter Inference for Diffusion MRI Signal Models.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Review
- A novel approach for dose painting radiotherapy of brain metastases guided by mr perfusion images.Frontiers in oncology · 2022Article
- [Consistency analysis between 3D arterial spin labeling and dynamic susceptibility contrast perfusion magnetic resonance imaging in perfusion imaging of brain tumor].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- A simulation study investigating potential diffusion-based MRI signatures of microstrokes.Scientific reports · 2021Article
- Non-Invasive MRI of Blood-Cerebrospinal Fluid Barrier Function.Nature communications · 2020Article
- Perfusion and apparent oxygenation in the human placenta (PERFOX).Magnetic resonance in medicine · 2020Article
- Non-contrast MR imaging of blood-brain barrier permeability to water.Magnetic resonance in medicine · 2018Article
- Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Review
- Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Review
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5 authors.
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Abstract
The study and clinical assessment of brain disease is currently hindered by a lack of non-invasive methods for the detailed and accurate evaluation of cerebral vascular pathology. Angiography can detect aberrant flow in larger feeding arteries/arterioles but cannot resolve the micro-vascular network. Small vessels are a key site of vascular pathology that can lead to haemorrhage and infarction, which may in turn trigger or exacerbate neurodegenerative processes. In this study, we describe a method to investigate microvascular flow anisotropy using a hybrid arterial spin labelling and multi-direction diffusion-weighted MRI sequence. We present evidence that the technique is sensitive to the mean/predominant direction of microvascular flow in localised regions of the rat cortex. The data provide proof of principle for a novel and non-invasive imaging tool to investigate cerebral micro-vascular flow patterns in healthy and disease states.
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