Evidence map›Paper›PMID 27461794›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2016

Impact of Body Mass Index on Outcomes in Cardiac Surgery.

Mei Gao, Jianzhong Sun, Nilas Young, Douglas Boyd, Zane Atkins, Zhongmin Li, Qian Ding, James Diehl, Hong Liu

Abstract readMulticenter Study
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Long-Term Impact of a Teleprehabilitation Programme on Modifiable Risk Factors and Quality of Life After Cardiac Surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
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  16. Association of body mass index with 30-day mortality and red blood cell transfusions in open heart surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mei GaoDepartment of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China; Department of Anesthesiology and Pain Medicine, University of California Davis Health System, Sacramento, CA.
Jianzhong SunDepartment of Anesthesiology, Thomas Jefferson University and Hospitals, Philadelphia, PA.
Nilas YoungDepartments of §Surgery and.
Douglas BoydDepartments of §Surgery and.
Zane AtkinsDepartments of §Surgery and.
Zhongmin LiInternal Medicine, University of California Davis Health System, Sacramento, CA.
Qian DingDepartment of Anesthesiology, Thomas Jefferson University and Hospitals, Philadelphia, PA; Department of Anesthesiology, The Fourth Military Medical University, Xian, China.
James DiehlDivision of Cardiothoracic Surgery, Thomas Jefferson University and Hospitals, Philadelphia, PA.
Hong LiuDepartment of Anesthesiology, Thomas Jefferson University and Hospitals, Philadelphia, PA. Electronic address: hualiu@ucdavis.edu.

Funding

UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
NCATS NIH HHS UL1 TR000002
6 · The paper itself

Abstract

objectivesBody mass index (BMI) commonly is used in obesity classification as a surrogate measure, and obesity is associated with a cluster of risk factors for cardiovascular disease. The aim of this study was to investigate the impact of BMI on short-term outcomes after cardiac surgery.

designA retrospective cohort study.

settingUniversity teaching hospital, 2 centers.

participantsThe study comprised 4,740 patients who underwent cardiac surgery at 2 hospitals-from July 1, 2001, to June 30, 2013, in 1 hospital and from September 1, 2003, to August 31, 2014, in a second hospital.

interventionsNo changes to standard practice were required. MEASUREMENTS AND MAIN

resultsPatients were assigned into 6 BMI groups as follows: underweight (BMI<18.5 kg/m(2)), normal weight (≥18.5 to<25 kg/m(2)), overweight (≥25 to<30 kg/m(2)), class I obese (≥30 to<35 kg/m(2)), class II obese (≥35 to<40 kg/m(2)), and class III obese (BMI≥40 kg/m(2)). Short-term major postoperative complications (postoperative stroke, cardiac arrest, new atrial fibrillation/flutter, permanent rhythm device insertion, deep sternal infection, sepsis, prolonged ventilation, pneumonia, renal dialysis, renal failure, intensive care unit readmission, total intensive care unit hours, and readmission in 30 days, and mortalities (in-hospital mortality, 30-day mortality, surgical mortality) were compared among various BMI groups after cardiac surgery. Age, sex, surgery type, family history of coronary artery disease, diabetes, hypertension, heart failure, and lipid-lowering medication were the risk factors for early outcomes. Multiple logistic regression analysis indicated that the underweight and class III obese BMI groups demonstrated significant, adverse differences in some short-term outcomes, including deep sternal infection, prolonged ventilation, new atrial fibrillation/flutter, and renal failure. However, being in the overweight or class I obese group demonstrated a positive effect on discharge and surgical mortality.

conclusionsThe results of this study demonstrated that extreme obesity and underweight were significantly associated with early major adverse clinical outcomes. However, there was an "obese paradox" in short-term mortality after cardiac surgery.

Indexed as

Body Mass IndexCardiac Surgical ProceduresPostoperative ComplicationsCohort StudiesFemaleHumansMaleMiddle AgedObesityRetrospective StudiesThinnessTreatment Outcomebody mass indexcardiac surgerymortalityobeseoutcome

Identifiers

PMID27461794
PMCPMC5011022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.