Evidence map›Paper›PMID 27461784›Full record

ArticleDento maxillo facial radiology2016

Dose reduction potential of iterative reconstruction algorithms in neck CTA-a simulation study.

Stephan Ellmann, Ferdinand Kammerer, Thomas Allmendinger, Michael Brand, Rolf Janka, Matthias Hammon, Michael M Lell, Michael Uder, Manuel Kramer

Open access · greenAbstract read
In one paragraph

Article in Dento maxillo facial radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephan Ellmann1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.ORCID http://orcid.org/0000-0003-2737-5526
Ferdinand Kammerer1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Thomas Allmendinger2 Siemens Healthineers GmbH, CT Division, Siemensstraße 1, Forchheim/Erlangen, Germany.
Michael Brand1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Rolf Janka1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Matthias Hammon1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Michael M Lell3 Clinicum Nuernberg, Department of Radiology and Nuclear Medicine, Paracelsus Medical University, Nuremberg, Germany.
Michael Uder1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Manuel Kramer1 Institute of Radiology, University Hospital Erlangen-Nuernberg, University of Erlangen-Nuernberg, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEParacelsus Medizinische Privatuniversität · DESiemens Healthineers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to determine the degree of radiation dose reduction in neck CT angiography (CTA) achievable with Sinogram-affirmed iterative reconstruction (SAFIRE) algorithms.

methods10 consecutive patients scheduled for neck CTA were included in this study. CTA images of the external carotid arteries either were reconstructed with filtered back projection (FBP) at full radiation dose level or underwent simulated dose reduction by proprietary reconstruction software. The dose-reduced images were reconstructed using either SAFIRE 3 or SAFIRE 5 and compared with full-dose FBP images in terms of vessel definition. 5 observers performed a total of 3000 pairwise comparisons.

resultsSAFIRE allowed substantial radiation dose reductions in neck CTA while maintaining vessel definition. The possible levels of radiation dose reduction ranged from approximately 34 to approximately 90% and depended on the SAFIRE algorithm strength and the size of the vessel of interest. In general, larger vessels permitted higher degrees of radiation dose reduction, especially with higher SAFIRE strength levels. With small vessels, the superiority of SAFIRE 5 over SAFIRE 3 was lost.

conclusionsNeck CTA can be performed with substantially less radiation dose when SAFIRE is applied. The exact degree of radiation dose reduction should be adapted to the clinical question, in particular to the smallest vessel needing excellent definition.

Indexed as

AlgorithmsComputed Tomography AngiographyImage Processing, Computer-AssistedRadiation DosageComputer SimulationFemaleHumansMaleMiddle AgedNeckangiographycarotid artery, externalCT, spiralradiation dose

Identifiers

PMID27461784
PMCPMC5595027
OpenAlexW2501419538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.