Trial reportJournal of vascular and interventional radiology : JVIR2016
Prospective Randomized Trial for Image-Guided Biopsy Using Cone-Beam CT Navigation Compared with Conventional CT.
Trial report in Journal of vascular and interventional radiology : JVIR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01287013 (Prospective Randomized Trial Comparing Navigation With Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Randomized Trial Comparing Navigation With Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- A systematic review on the application of the hybrid operating room in surgery: experiences and challenges.Updates in surgery · 2022Pooled it
- Clinical evaluation of the effectiveness of laser localization system in CT-guided percutaneous lung puncture positioning: a prospective randomized controlled pilot study.Quantitative imaging in medicine and surgery · 2026Article
- Cone-Beam Computed Tomography Laser-Guided Transthoracic Needle Biopsy for Pulmonary Lesions in a Hybrid Operating Room: Feasibility Study by an Interventional Pulmonologist.Diagnostics (Basel, Switzerland) · 2026Article
- Investigating 4D respiratory cone-beam CT imaging for thoracic interventions on robotic C-arm systems: a deformable phantom study.Physical and engineering sciences in medicine · 2024Article
- Universal non-circular cone beam CT orbits for metal artifact reduction imaging during image-guided procedures.Scientific reports · 2024Article
- Cone Beam Computed Tomography for the Interventional Oncologist: A Practical Approach.Seminars in interventional radiology · 2024Review
- Fully automatic online geometric calibration for non-circular cone-beam CT orbits using fiducials with unknown placement.Medical physics · 2024Article
- Chinese expert consensus on cone-beam CT-guided diagnosis, localization and treatment for pulmonary nodules.Thoracic cancer · 2024Article
- Percutaneous microwave ablation for lung tumors: a retrospective case-control study of conventional CT and C-arm CT guidance.Quantitative imaging in medicine and surgery · 2023Article
- Using 3D polylines to improve cone-beam CT-guided percutaneous transthoracic needle biopsy.The British journal of radiology · 2022Article
- Combining Shape-Sensing Robotic Bronchoscopy With Mobile Three-Dimensional Imaging to Verify Tool-in-Lesion and Overcome Divergence: A Pilot Study.Mayo Clinic proceedings. Innovations, quality & outcomes · 2022Article
- C-Arm Cone-Beam CT Virtual Navigation versus Conventional CT Guidance in the Transthoracic Lung Biopsy: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2022Article
- Advances in Diagnostic Bronchoscopy.Diagnostics (Basel, Switzerland) · 2021Review
- Cone-Beam CT-Guided Lung Biopsies: Results in 94 Patients.Diagnostics (Basel, Switzerland) · 2020Article
- Cone beam navigation bronchoscopy: the next frontier.Journal of thoracic disease · 2020Review
- Diagnostic Accuracy of Percutaneous Transthoracic Needle Lung Biopsies: A Multicenter Study.Korean journal of radiology · 2019Article
- Cone-Beam CT With Augmented Fluoroscopy Combined With Electromagnetic Navigation Bronchoscopy for Biopsy of Pulmonary Nodules.Journal of bronchology & interventional pulmonology · 2018Article
- Cone beam computed tomography virtual navigation-guided transthoracic biopsy of small (≤ 1 cm) pulmonary nodules: impact of nodule visibility during real-time fluoroscopy.The British journal of radiology · 2018Article
- Risk factors for haemoptysis after percutaneous transthoracic needle biopsies in 4,172 cases: Focusing on the effects of enlarged main pulmonary artery diameter.European radiology · 2018Article
- Recent advances in diagnostic bronchoscopy.Journal of thoracic disease · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo compare cone-beam computed tomography (CT) navigation vs conventional CT image guidance during biopsies. MATERIALS AND
methodsPatients scheduled for image-guided biopsies were prospectively and randomly assigned to conventional CT guidance vs cone-beam CT navigation. Radiation dose, accuracy of final needle position, rate of histopathologic diagnosis, and number of needle repositions to reach the target (defined as pullback to adjust position) were compared.
resultsA total of 58 patients (mean age, 57 y; 62.1% men) were randomized: 29 patients underwent 33 biopsies with CT guidance and 29 patients with 33 lesions underwent biopsy with cone-beam CT navigation. The average body mass index (BMI) was similar between groups, at 28.8 kg/m(2) ± 6.55 (P = .18). There was no difference between groups in terms of patient and lesion characteristics (eg, size, depth). The average lesion size was 29.1 ± 12.7mm for CT group vs 32.1mm ±16.8mm for cone-beam CT group (P < 0.59). Location of lesions was equally divided between the 2 groups, 20 lung lesions, 18 renal lesions and 20 other abdominal lesions. Mean number of needle repositions in the cone-beam CT group was 0.3 ± 0.5, compared with 1.9 ± 2.3 with conventional CT (P < .001). The average skin entry dose was 29% lower with cone-beam CT than with conventional CT (P < .04 accounting for BMI). The average estimated effective dose for the planning scan from phantom data was 49% lower with cone-beam CT vs conventional CT (P = .018). Accuracy, defined as the difference between planned and final needle positions, was 4.9 mm ± 4.1 for the cone-beam CT group, compared with 12.2 mm ± 8.1 for conventional CT (P < .001). Histopathologic diagnosis rates were similar between groups, at 90.9% for conventional CT and 93.9% for cone-beam CT (P = .67).
conclusionsCone-beam CT navigation for biopsies improved targeting accuracy with fewer needle repositions, lower skin entry dose, and lower effective dose for planning scan, and a comparable histopathologic diagnosis rate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.