ArticleScientific reports2016
Genomic epidemiology and global diversity of the emerging bacterial pathogen Elizabethkingia anophelis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
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Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Unraveling the global landscape of Elizabethkingia antibiotic resistance: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Mortality Risk and Antibiotic Therapy for Patients with Infections Caused byMedicina (Kaunas, Lithuania) · 2024Pooled it
- Elizabethkingia in Children: A Comprehensive Review of Symptomatic Cases Reported From 1944 to 2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Pooled it
- Divergent roles of OmpA family proteins in physiology, stress tolerance, and virulence ofVirulence · 2026Article
- Molecular epidemiology and emergingAntimicrobial agents and chemotherapy · 2026Article
- Mapping the evolutionary and translational landscape of antibiotic resistance genes in Elizabethkingia anopheles.Molecular genetics and genomics : MGG · 2026Article
- From cognition to response: clinical challenges, antibiotic resistance mechanisms, and prevention and control strategies ofFrontiers in microbiology · 2026Review
- Article
- Article
- Genomic profiling ofFrontiers in microbiology · 2025Article
- Molecular characterization, comparative genome analysis and resistance determinants of three clinicalFrontiers in microbiology · 2025Article
- Cefiderocol-ResistantCase reports in infectious diseases · 2025Article
- Linalool exhibit antimicrobial ability againstCurrent research in microbial sciences · 2025Article
- Antimicrobial Susceptibility Patterns and Antimicrobial Therapy of Infections Caused byMedicina (Kaunas, Lithuania) · 2024Review
- capD deletion in the Elizabethkingia miricola capsular locus leads to capsule production deficiency and reduced virulence.Veterinary research · 2024Article
- Large-scale genomic analysis of Elizabethkingia anophelis.BMC genomics · 2024Article
- Epidemiology, clinical profiles, and antimicrobial susceptibility ofSaudi medical journal · 2024Article
- Article
- Whole-genome sequence and resistance determinants of four Elizabethkingia anophelis clinical isolates collected in Hanoi, Vietnam.Scientific reports · 2024Article
- Identification and characterization of CIM-1, a carbapenemase that adds to the family of resistance factors against last resort antibiotics.Communications biology · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Elizabethkingia anophelis is an emerging pathogen involved in human infections and outbreaks in distinct world regions. We investigated the phylogenetic relationships and pathogenesis-associated genomic features of two neonatal meningitis isolates isolated 5 years apart from one hospital in Central African Republic and compared them with Elizabethkingia from other regions and sources. Average nucleotide identity firmly confirmed that E. anophelis, E. meningoseptica and E. miricola represent demarcated genomic species. A core genome multilocus sequence typing scheme, broadly applicable to Elizabethkingia species, was developed and made publicly available (http://bigsdb.pasteur.fr/elizabethkingia). Phylogenetic analysis revealed distinct E. anophelis sublineages and demonstrated high genetic relatedness between the African isolates, compatible with persistence of the strain in the hospital environment. CRISPR spacer variation between the African isolates was mirrored by the presence of a large mobile genetic element. The pan-genome of E. anophelis comprised 6,880 gene families, underlining genomic heterogeneity of this species. African isolates carried unique resistance genes acquired by horizontal transfer. We demonstrated the presence of extensive variation of the capsular polysaccharide synthesis gene cluster in E. anophelis. Our results demonstrate the dynamic evolution of this emerging pathogen and the power of genomic approaches for Elizabethkingia identification, population biology and epidemiology.
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