ArticlePediatric surgery international2016
Risk factors and prevention for surgical intestinal disorders in extremely low birth weight infants.
Article in Pediatric surgery international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Risk factors for necrotizing enterocolitis in neonates: a systematic review of prognostic studies.BMC pediatrics · 2017Pooled it
- Erythropoietin prevents necrotizing enterocolitis in very preterm infants: a randomized controlled trial.Journal of translational medicine · 2020Trial
- Placental Insufficiency and Neonatal Vulnerability: Organ-Specific Mechanisms Shaping Early-Life Health.The journal of obstetrics and gynaecology research · 2026Review
- Meconium obstruction of prematurity in tiny babies - towards developing an international consensus.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Doppler abnormality predisposes preterm infants with fetal growth restriction to postnatal intestinal disorder.The journal of obstetrics and gynaecology research · 2025Article
- Aggressive enema and surgery for meconium-related ileus in extremely low-birth-weight infants.Pediatric surgery international · 2025Article
- Host-derived protein profiles of human neonatal meconium across gestational ages.Nature communications · 2024Article
- Does protocol miconazole administration improve mortality and morbidity on surgical necrotizing enterocolitis?Pediatric surgery international · 2023Article
- Article
- Successful staged repair of pulmonary atresia, ventricular septal defect, and major aortopulmonary collateral arteries in an extremely low birth weight infant.General thoracic and cardiovascular surgery · 2020Article
- Risk factors of meconium-related ileus in very low birth weight infants: patients-control study.Scientific reports · 2020Article
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSurgical intestinal disorders (SID), such as necrotizing enterocolitis (NEC), focal intestinal perforation (FIP), and meconium-related ileus (MRI), are serious morbidities in extremely low birth weight (ELBW, birth weight <1000 g) infants. From 2010, we performed enteral antifungal prophylaxis (EAP) in ELBWI to prevent for SID. The aim of this study was to identify disease-specific risk factors and to evaluate the efficacy of prevention for SID in ELBW infants.
methodsA retrospective chart review of all consecutive patients between January 2006 and March 2015, which included 323 ELBW infants who were admitted to Shizuoka Children's Hospital, was conducted.
resultsThe number of infants with NEC, FIP, and MRI was 9, 12, and 13, respectively; 28 in 323 ELBW infants died. The control group defined the cases were not SID. In-hospital mortality was higher in infants with NEC relative to those in the control group. On logistic regression analysis, low gestational age and cardiac malformations were associated with increased risk of NEC. IUGR were associated with increased risk of MRI. EAP decreased risk of NEC and FIP. Low gestational weight and NEC were associated with increased risk of death.
conclusionSurvival to hospital discharge after operation for NEC in ELBW infants remains poor. EAP decreased risk of NEC and FIP in ELBW infants.
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