ArticleAIDS care2017
Poor retention in early care increases risk of mortality in a Brazilian HIV-infected clinical cohort.
Article in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Retention in Care Among People Living with HIV in Nigeria: A Systematic Review and Meta-analysis.Journal of research in health sciences · 2024Pooled it
- Development and validation of a mortality risk prediction index score for adults living with HIV and multiple chronic comorbidities.International journal of population data science · 2025Article
- Outcomes of severely ill patients with AIDS treated with efavirenz or dolutegravir: a multicenter, observational study.Frontiers in medicine · 2024Article
- Real-world effectiveness of WHO recommended first-line antiretroviral therapies: a cohort study from a middle-income country.AIDS care · 2023Article
- Impact of an intensive facility-community case management intervention on 6-month HIV outcomes among select key and priority populations in Uganda.AIDS research and therapy · 2022Article
- The Effect of Partnership Presence and Support on HIV Viral Suppression Among Serodiscordant Partnered and Single Heterosexual HIV-Positive Individuals in Brazil.AIDS and behavior · 2021Article
- Late initiation of antiretroviral therapy: inequalities by educational level despite universal access to care and treatment.BMC public health · 2021Article
- The Population Impact of Late Presentation With Advanced HIV Disease and Delayed Antiretroviral Therapy in Adults Receiving HIV Care in Latin America.American journal of epidemiology · 2020Article
- Compound Retention in Care and All-Cause Mortality Among Persons Living With Human Immunodeficiency Virus.Open forum infectious diseases · 2019Article
- Early Retention in Care Neither Mediates Nor Modifies the Effect of Sex and Sexual Mode of HIV Acquisition on HIV Survival in the Americas.AIDS patient care and STDs · 2018Article
- Trends and disparities in retention to antiretroviral therapy of people living with HIV from 2014 to 2022 in Brazil: a population-based study.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Retention in early HIV care has been associated with decreased mortality and improved viral suppression, however the consequences of poor retention in early care in Brazil remain unknown. We assessed the effect of poor retention on mortality in a Brazilian HIV-infected clinical cohort. The analysis included ART-naïve, HIV-infected adults linked to care at the Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz between 2000 and 2010, who did not become pregnant nor participate in a clinical trial during the first two years in care (early care). Poor retention in early care was defined as less than 3 out of 4 six-month intervals with a CD4 or HIV-1 RNA laboratory result during early care. Cox proportional hazards models were used to identify factors associated with mortality, and Kaplan-Meier plots were used to describe the survival probability for participants with poor retention versus good retention. Among 1054 participants with a median (interquartile range) follow-up time of 4.2 years (2.6, 6.3), 20% had poor retention in early care and 8% died. Poor retention in early care [adjusted hazard ratio (aHR) 3.09; 95% CI 1.65-5.79], AIDS defining illness (aHR 1.95; 95% CI 1.20-3.18) and lower education (aHR 2.33; 95% CI 1.45-3.75) were associated with increased mortality risk. Our findings highlight the importance of adopting strategies to improve retention in early HIV care.
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