ArticleBiomacromolecules2016
Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers.
Article in Biomacromolecules, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Contrast Agent Design to Deliver Improved Ultrasound Echogenicity from Medical Devices: A Route to In-Ward Device Placement Tracking.Biomacromolecules · 2026Article
- A Prospective Multicenter Randomized Study to Assess the Impact of a Novel Catheter Coating on Clinical Bacteriuria.Antibiotics (Basel, Switzerland) · 2026Article
- Bioinstructive polymer fibre mats to reduce bacterial pathogen colonisation.RSC applied polymers · 2026Article
- Silicone Films Modified with Ethylene Glycol Dicyclopentenyl Ether Acrylate for Antimicrobial Silver Loading.Polymers · 2025Article
- Fungal Attachment-Resistant Polymers for the Additive Manufacture of Medical Devices.ACS applied materials & interfaces · 2024Article
- Predictive Molecular Design and Structure-Property Validation of Novel Terpene-Based, Sustainably Sourced Bacterial Biofilm-Resistant Materials.Biomacromolecules · 2023Article
- Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation.Science advances · 2023Article
- Recent advances in the medical applications of hemostatic materials.Theranostics · 2023Review
- Facile Synthesis of Functionalised Hyperbranched Polymers for Application as Novel, Low Viscosity Lubricant Formulation Components.Polymers · 2022Article
- Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Alginate Bioconjugate and Graphene Oxide in Multifunctional Hydrogels for Versatile Biomedical Applications.Molecules (Basel, Switzerland) · 2021Article
- Discovery of hemocompatible bacterial biofilm-resistant copolymers.Biomaterials · 2020Article
- Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration.Science advances · 2020Article
- Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections.Biomaterials science · 2020Article
- Ethylene Glycol Dicyclopentenyl (Meth)Acrylate Homo and Block Copolymers via Nitroxide Mediated Polymerization.Materials (Basel, Switzerland) · 2019Article
- Development and characterization of a stable adhesive bond between a poly(dimethylsiloxane) catheter material and a bacterial biofilm resistant acrylate polymer coating.Biointerphases · 2017Article
- Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting.ACS applied materials & interfaces · 2016Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
Abstract
Developing medical devices that resist bacterial attachment and subsequent biofilm formation is highly desirable. In this paper, we report the optimization of the molecular structure and thus material properties of a range of (meth)acrylate copolymers which contain monomers reported to deliver bacterial resistance to surfaces. This optimization allows such monomers to be employed within novel coatings to reduce bacterial attachment to silicone urinary catheters. We show that the flexibility of copolymers can be tuned to match that of the silicone catheter substrate, by copolymerizing these polymers with a lower Tg monomer such that it passes the flexing fatigue tests as coatings upon catheters, that the homopolymers failed. Furthermore, the Tg values of the copolymers are shown to be readily estimated by the Fox equation. The bacterial resistance performance of these copolymers were typically found to be better than the neat silicone or a commercial silver containing hydrogel surface, when the monomer feed contained only 25 v% of the "hit" monomer. The method of initiation (either photo or thermal) was shown not to affect the bacterial resistance of the copolymers. Optimized synthesis conditions to ensure that the correct copolymer composition and to prevent the onset of gelation are detailed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.