Evidence map›Paper›PMID 27461006›Full record

ArticleTrends in endocrinology and metabolism: TEM2016

Sirtuins in Cardiovascular Health and Diseases.

Suowen Xu, Peter Bai, Zheng Gen Jin

Abstract readLetterComment
In one paragraph

Article in Trends in endocrinology and metabolism: TEM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Inflammation and Vascular Ageing: From Telomeres to Novel Emerging Mechanisms.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Suowen XuAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14640, USA.
Peter BaiDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Lendület Laboratory of Cellular Metabolism Research Group, Debrecen, Hungary; Research Center for Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Zheng Gen JinAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14640, USA. Electronic address: zheng-gen_jin@urmc.rochester.edu.

Funding

SIRT6 and vascular endothelial homeostasisR01HL130167 · NHLBI · UNIVERSITY OF ROCHESTER · PI JIN, ZHENG-GEN · 2017 to 2025
$4.2M
Molecular regulation of angiogenesisR01HL114570 · NHLBI · UNIVERSITY OF ROCHESTER · PI JIN, ZHENG-GEN · 2012 to 2016
$1.9M
Regulation of angiogenesis by transcription factorsR01HL128363 · NHLBI · UNIVERSITY OF ROCHESTER · PI JIN, ZHENG-GEN · 2016 to 2019
$1.5M
Regulation of laminar flow atheroprotective genes by HDAC5R01HL109502 · NHLBI · UNIVERSITY OF ROCHESTER · PI JIN, ZHENG-GEN · 2012 to 2015
$1.5M
NHLBI NIH HHS R01 HL109502NHLBI NIH HHS R01 HL114570NHLBI NIH HHS R01 HL128363NHLBI NIH HHS R01 HL130167
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesSirtuinsAgingHumansSirtuinscardiac hypertrophysirtuinstherapeutic targetvascular disease

Identifiers

PMID27461006
PMCPMC5995322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.