ArticleBMC nephrology2016
Are low birth weight neonates at risk for suboptimal renal growth and function during infancy?
Article in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Protecting Kidney Health in the First 1000 Days: The Pediatrician's Role in Safeguarding the Weakest.Diseases (Basel, Switzerland) · 2026Review
- Maternal and fetal determinants on kidney size in early childhood: insights from a New York City cohort.BMC nephrology · 2026Article
- Shear-wave elastography in renal stiffness in children with hematuria and/or proteinuria.Pediatric research · 2025Article
- Parental fructose consumption induces early baroreflex dysfunction in offspring: impact on arterial pressure and on insulin resistance.International journal of obesity (2005) · 2024Article
- Role of foetal kidney size on kidney function in childhood: the born in bradford cohort renal study.BMC nephrology · 2023Article
- Urinary KIM-1 is not correlated with gestational age among 5-year-old children born prematurely.Frontiers in pediatrics · 2023Article
- Early-life factors and adult anti-Müllerian hormone levels.Journal of assisted reproduction and genetics · 2021Article
- Kidney function in patients with primary distal renal tubular acidosis.Pediatric nephrology (Berlin, Germany) · 2021Article
- The old becomes new: advances in imaging techniques to assess nephron mass in children.Pediatric nephrology (Berlin, Germany) · 2021Review
- Birth weight and renal markers in children aged 5-10 years in Cameroon: a cross-sectional study.BMC nephrology · 2020Article
- Birth weight influences the kidney size and function of Bangladeshi children.Journal of developmental origins of health and disease · 2018Article
- A population pharmacokinetic model for individualised dosage regimens of vancomycin in Chinese neonates and young infants.Oncotarget · 2017Article
- Low birth weight is associated with impaired murine kidney development and function.Pediatric research · 2017Article
- Renal deficit and associated factors in children born with low birth weight.Jornal brasileiro de nefrologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess the renal growth and function of neonates during infancy in relation to birth weight and gestational age.
methodsA longitudinal study was conducted at a tertiary hospital in South India from June 2010 to August 2014. Low birth weight neonates (LBW) were further sub-classified based on gestational age and compared with normal birth weight (NBW) full term neonates at birth, 6 months and 18-24months of age. The renal volume was measured by ultrasound and renal function by Cystatin C- derived glomerular filtration rate (CysGFR) at the three time points during the dynamic phase of renal maturation in infancy.
resultsWe recruited 100 LBW and 66 NBW term neonates. Thirty five percent of the LBW neonates were SGA. Among the AGA neonates, 39 % were LBW neonates. The mean height and weight of the LBW neonates were significantly lower compared to NBW neonates throughout infancy. The increment in kidney volume was in accordance with the change in body size, being lower in LBW compared to NBW infants. The combined kidney volume was significantly lower in LBW and SGA neonates across all three time points (p < 0.001). CysGFR in the LBW and SGA infants, despite having low kidney volumes, were comparable to the GFRs of NBW and AGA neonates at the end of infancy.
conclusionThis study highlights the fact that both birth weight and gestational age influence kidney growth and function in infancy. At the end of infancy, despite a significant difference in kidney volumes and age at last follow up, the glomerular filtration rate was comparable between LBW and NBW infants. Though not statistically significant, there was a trend towards higher urine microalbumin in LBW compared to NBW in infancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.