Evidence map›Paper›PMID 27460427›Full record

ArticleDiagnostic microbiology and infectious disease2016

A comparison of flocked swabs and traditional swabs, using multiplex real-time PCR for detection of common gastroenteritis pathogens in Botswana.

Margaret Mokomane, Ishmael Kasvosve, Simani Gaseitsiwe, Andrew P Steenhoff, Jeffrey M Pernica, Kwana Lechiile, Kathy Luinstra, Marek Smieja, David M Goldfarb

Abstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margaret MokomaneDepartment of Medical Laboratory Sciences, Faculty of Health Sciences University of Botswana, Gaborone, Botswana; Botswana National Health Laboratory, Gaborone, Botswana. Electronic address: bafanamargaret@gmail.com.
Ishmael KasvosveDepartment of Medical Laboratory Sciences, Faculty of Health Sciences University of Botswana, Gaborone, Botswana.
Simani GaseitsiweBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Andrew P SteenhoffBotswana-UPenn Partnership, Gaborone, Botswana; Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Jeffrey M PernicaMcMaster University, Hamilton, Ontario, Canada.
Kwana LechiileBotswana-UPenn Partnership, Gaborone, Botswana.
Kathy LuinstraSt Joseph's Healthcare, Hamilton, Ontario, Canada.
Marek SmiejaMcMaster University, Hamilton, Ontario, Canada.
David M GoldfarbMcMaster University, Hamilton, Ontario, Canada; University of British Columbia, Vancouver, Canada.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
NIAID NIH HHS P30 AI045008
6 · The paper itself

Abstract

We compared the performance of flocked and matched traditional rectal swabs collected from 236 children admitted with gastroenteritis in Botswana. All samples were tested using real time multiplex-PCR assays for nine enteric pathogens. There was a 20% higher detection of Shigella from flocked swabs, but most other pathogens had similar detection rates.

Indexed as

AnimalsBacteriaBotswanaChild, PreschoolFemaleGastroenteritisHumansInfantMaleMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionParasitesReal-Time Polymerase Chain ReactionSensitivity and SpecificitySpecimen HandlingVirusesFlocked swabsGastroenteritisMcNemar exact testMultiplex PCRShigellaThreshold cycle

Identifiers

PMID27460427
PMCPMC5028275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.