Evidence map›Paper›PMID 27460017›Full record

ArticleActa neuropathologica2016

The pathogenic relevance of α

Chaoling Dong, Steven P Palladino, Eric Scott Helton, Eroboghene E Ubogu

Open access · greenAbstract read
In one paragraph

Article in Acta neuropathologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  5. Review
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  10. Review
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  13. Article
  14. Immunotherapy of Guillain-Barré syndrome.Human vaccines & immunotherapeutics · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Novel pathomechanisms in inflammatory neuropathies.Journal of neuroinflammation · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chaoling DongNeuromuscular Immunopathology Research Laboratory, Division of Neuromuscular Disease, Department of Neurology, University of Alabama at Birmingham, 1720 7th Avenue South, Sparks Center 200, Birmingham, AL, 35294-0017, USA.
Steven P PalladinoNeuromuscular Immunopathology Research Laboratory, Division of Neuromuscular Disease, Department of Neurology, University of Alabama at Birmingham, 1720 7th Avenue South, Sparks Center 200, Birmingham, AL, 35294-0017, USA.
Eric Scott HeltonNeuromuscular Immunopathology Research Laboratory, Division of Neuromuscular Disease, Department of Neurology, University of Alabama at Birmingham, 1720 7th Avenue South, Sparks Center 200, Birmingham, AL, 35294-0017, USA.
Eroboghene E UboguNeuromuscular Immunopathology Research Laboratory, Division of Neuromuscular Disease, Department of Neurology, University of Alabama at Birmingham, 1720 7th Avenue South, Sparks Center 200, Birmingham, AL, 35294-0017, USA. eeubogu@uabmc.edu.ORCID 0000-0002-8307-9994
University of Alabama at Birmingham · US

Funding

Alpha M Beta 2 integrin blockade for acute inflammatory neuropathiesR21NS078226 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UBOGU, EROBOGHENE EKAMERENO · 2012 to 2013
$424k
NINDS NIH HHS R21 NS078226
6 · The paper itself

Abstract

The molecular determinants and mechanisms involved in leukocyte trafficking across the blood-nerve barrier (BNB) in the acute inflammatory demyelinating polyradiculoneuropathy (AIDP) variant of Guillain-Barré syndrome are incompletely understood. Prior work using a flow-dependent in vitro human BNB model demonstrated a crucial role for α

Indexed as

AnimalsAntibodiesAntigens, CDAntigens, DifferentiationCD11b AntigenCell TrackingDisease Models, AnimalElectric StimulationFemaleFlow CytometryGene Expression RegulationGuillain-Barre SyndromeHumansImmunoglobulins, IntravenousLeukocytesMaleAntibodiesAntigens, CDAntigens, DifferentiationCD11b AntigenImmunoglobulins, Intravenousmonocyte-macrophage differentiation antigenneurofilament protein HNeurofilament ProteinsS100 Calcium Binding Protein beta SubunitAcute inflammatory demyelinating polyradiculoneuropathyBlood–nerve barrierCD11bExperimental autoimmune neuritisGuillain–Barré syndromeIntegrin

Identifiers

PMID27460017
PMCPMC5074851
OpenAlexW2499657723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.