ReviewRadiation research2016
Extracellular Vesicles and Vascular Injury: New Insights for Radiation Exposure.
Review in Radiation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Integrated Epidemiological and Extracellular Vesicle Profiling Identifies miR-126-3p, miR-21-5p, miR-92a-3p and SNAIL as Candidate Biomarkers of Endothelial Dysfunction and Cardio-Metabolic Risk.International journal of molecular sciences · 2026Article
- Extracellular Vesicles in Obesity: From Pathophysiological Mediators to Therapeutic Tools.International journal of molecular sciences · 2026Review
- Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol.Journal of extracellular biology · 2025Article
- Review
- Endothelial Cell Derived Extracellular Vesicles and Hematopoiesis.Radiation research · 2024Review
- Prognostic significance of circulating microparticles in IgA nephropathy.International urology and nephrology · 2024Article
- Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.Bone research · 2024Article
- Osteoblast Derived Exosomes Alleviate Radiation- Induced Hematopoietic Injury.Frontiers in bioengineering and biotechnology · 2022Article
- Promise of extracellular vesicles for diagnosis and treatment of epilepsy.Epilepsy & behavior : E&B · 2021Review
- Radiation Can Regulate the Expression of miRNAs Associated with Osteogenesis and Oxidation in Exosomes from Peripheral Blood Plasma.Oxidative medicine and cellular longevity · 2021Article
- Extracellular Vesicles for the Treatment of Radiation Injuries.Frontiers in pharmacology · 2021Review
- Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/Stem cells international · 2021Article
- Cutaneous Radiation Injuries: Models, Assessment and Treatments.Radiation research · 2020Article
- The Interstitial System of the Brain in Health and Disease.Aging and disease · 2020Review
- Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain.International journal of molecular sciences · 2019Article
- Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.International journal of radiation oncology, biology, physics · 2019Article
- New therapeutic insights into radiation-induced myocardial fibrosis.Therapeutic advances in chronic disease · 2019Review
- Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer: Protocol for a European Multicenter Prospective Cohort Study (MEDIRAD EARLY HEART Study).JMIR research protocols · 2018Article
- Response to the 'Comments on "Cellular Therapies for Treatment of Radiation Injury after a Mass Casualty Incident" (Radiat Res 2017; 188:242-45)' by Drouet et al. (Letters to the Editor, Radiat Res 2017; 188:463).Radiation research · 2018Article
- Biological basis of radiation protection needs rejuvenation.International journal of radiation biology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
This article reviews our current knowledge about cell-derived extracellular vesicles (EVs), including microparticles and exosomes, and their emergence as mediators of a new important mechanism of cell-to-cell communication. Particular emphasis has been given to the increasing involvement of EVs in the field of radiation-induced vascular injury. Although EVs have been considered for a long time as cell "dust", they in fact precisely reflect the physiological state of the cells. The role of microparticles and exosomes in mediating vascular dysfunction suggests that they may represent novel pathways in short- or long-distance paracrine intercellular signaling in vascular environment. In this article, the mechanisms involved in the biogenesis of microparticles and exosomes, their composition and participation in the pathogenesis of vascular dysfunction are discussed. Furthermore, this article highlights the concept of EVs as potent vectors of biological information and protagonists of an intercellular communication network. Special emphasis is made on EV-mediated microRNA transfer and on the principal consequences of such signal exchange on vascular injury and radiation-induced nontargeted effect. The recent progress in elucidating the biology of EVs has provided new insights for the field of radiation, advancing their use as diagnostic biomarkers or in therapeutic interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.