Evidence map›Paper›PMID 27459456›Full record

ReviewAmerican journal of public health2016

Breast Cancer Research in the Nurses' Health Studies: Exposures Across the Life Course.

Megan S Rice, A Heather Eliassen, Susan E Hankinson, Elizabeth B Lenart, Walter C Willett, Rulla M Tamimi

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. The Women's Soccer Health Study: From Head to Toe.Sports medicine (Auckland, N.Z.) · 2023
    Article
  7. Alterations in Pregnenolone and Testosterone Levels in Male Shift Workers.International journal of environmental research and public health · 2023
    Article
  8. Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Particulate Matter and Traffic-Related Exposures in Relation to Breast Cancer Survival.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  15. Article
  16. Article
  17. Advances in circular RNAs and their roles in breast Cancer.Journal of experimental & clinical cancer research : CR · 2018
    Review
  18. Breast Cancer Risk Factors: a Cross- Cultural Comparison between the West and the EastAsian Pacific journal of cancer prevention : APJCP · 2018
    Article
  19. Research Strategies for Nutritional and Physical Activity Epidemiology and Cancer Prevention.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Megan S RiceMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
A Heather EliassenMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
Susan E HankinsonMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
Elizabeth B LenartMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
Walter C WillettMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
Rulla M TamimiMegan S. Rice is with the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA. A. Heather Eliassen and Rulla M. Tamimi are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston. Elizabeth B. Lenart and Walter C. Willett are with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Susan E. Hankinson is with the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst.
Brigham and Women's Hospital · US

Funding

Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Life Course Cancer Epidemiology Cohort in WomenUM1CA176726 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2013 to 2017
$15.7M
Premonopausal Hormone Levels and Risk of Breast CancerR01CA067262 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HANKINSON, SUSAN E · 2002 to 2011
$11.9M
BIOCHEMICAL MARKERS IN THE NURSES'HEALTH STUDY COHORTR01CA049449 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E · 1989 to 2008
$11.3M
NCI NIH HHS P01 CA087969NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA067262NCI NIH HHS UM1 CA176726NCI NIH HHS UM1 CA186107
6 · The paper itself

Abstract

objectivesTo review the contribution of the Nurses' Heath Study (NHS) and the NHS II in identifying risk and protective factors for breast cancer incidence and survival.

methodsWe conducted a narrative review of NHS and NHS II articles on breast cancer incidence and survival published from 1976 to 2016, with a focus on exogenous and endogenous hormones; lifestyle factors, including diet, physical activity, and aspirin use; intermediate markers of risk; and genetic factors.

resultsWith the investigation of individual risk factors, as well as their incorporation into risk prediction models, the NHS has contributed to the identification of ways in which women may reduce breast cancer risk, including limiting alcohol consumption, reducing the duration of postmenopausal estrogen-plus-progestin use, avoiding weight gain, and increasing vegetable consumption. In addition, the NHS has helped elucidate the roles of several biomarkers and contributed to the identification of risk alleles.

conclusionsThe NHS has contributed to our understanding of lifestyle, hormonal, and genetic risk factors for breast cancer, highlighting the importance of exposures across the life course, and has helped identify lifestyle changes that may reduce risk and improve survival after a diagnosis of breast cancer.

Indexed as

NursesAdultBreast NeoplasmsEpidemiologic StudiesFemaleHumansLife StyleLongitudinal StudiesMiddle AgedProspective StudiesRisk FactorsUnited StatesWomen's Health

Identifiers

PMID27459456
PMCPMC4981804
OpenAlexW2482968479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.