Evidence map›Paper›PMID 27459455›Full record

ReviewAmerican journal of public health2016

Key Findings on Alcohol Consumption and a Variety of Health Outcomes From the Nurses' Health Study.

Elizabeth Mostofsky, Kenneth J Mukamal, Ed L Giovannucci, Meir J Stampfer, Eric B Rimm

Open access · greenAbstract readReview
In one paragraph

Review in American journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  8. Smoking and Alcohol Consumption and Risk of Incident Diverticulitis in Women.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
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  17. Alcohol Withdrawal and the Associated Mood Disorders-A Review.International journal of molecular sciences · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elizabeth MostofskyElizabeth Mostofsky is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, and the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Kenneth J. Mukamal is with the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center. Kenneth J. Mukamal is also with the Department of Nutrition, Harvard T. H. Chan School of Public Health. Ed L. Giovannucci, Meir J. Stampfer, and Eric B. Rimm are with the Department of Nutrition, Harvard T. H. Chan School of Public Health and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston.
Kenneth J MukamalElizabeth Mostofsky is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, and the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Kenneth J. Mukamal is with the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center. Kenneth J. Mukamal is also with the Department of Nutrition, Harvard T. H. Chan School of Public Health. Ed L. Giovannucci, Meir J. Stampfer, and Eric B. Rimm are with the Department of Nutrition, Harvard T. H. Chan School of Public Health and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston.
Ed L GiovannucciElizabeth Mostofsky is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, and the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Kenneth J. Mukamal is with the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center. Kenneth J. Mukamal is also with the Department of Nutrition, Harvard T. H. Chan School of Public Health. Ed L. Giovannucci, Meir J. Stampfer, and Eric B. Rimm are with the Department of Nutrition, Harvard T. H. Chan School of Public Health and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston.
Meir J StampferElizabeth Mostofsky is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, and the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Kenneth J. Mukamal is with the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center. Kenneth J. Mukamal is also with the Department of Nutrition, Harvard T. H. Chan School of Public Health. Ed L. Giovannucci, Meir J. Stampfer, and Eric B. Rimm are with the Department of Nutrition, Harvard T. H. Chan School of Public Health and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston.
Eric B RimmElizabeth Mostofsky is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, and the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Kenneth J. Mukamal is with the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center. Kenneth J. Mukamal is also with the Department of Nutrition, Harvard T. H. Chan School of Public Health. Ed L. Giovannucci, Meir J. Stampfer, and Eric B. Rimm are with the Department of Nutrition, Harvard T. H. Chan School of Public Health and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston.
Harvard University · USThe Huntington Library, Art Museum, and Botanical Gardens · US

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Life Course Cancer Epidemiology Cohort in WomenUM1CA176726 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2013 to 2017
$15.7M
Harvard Clinical and Translational Science CenterKL2TR001100 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$8.5M
NCATS NIH HHS KL2 TR001100NCI NIH HHS UM1 CA176726NCI NIH HHS UM1 CA186107NHLBI NIH HHS L30 HL115623
6 · The paper itself

Abstract

objectivesTo review critical contributions from the Nurses' Health Study (NHS) on alcohol consumption and health outcomes.

methodsWe performed a narrative review of NHS (1980-2012) and NHS II (1989-2011) publications.

resultsUsing detailed information on self-reported alcohol drinking patterns obtained approximately every 4 years combined with extensive information on diet, lifestyle habits, and physician-diagnosed health conditions, NHS investigators have prospectively examined the risks and benefits associated with alcohol consumption. Moderate intake, defined as up to 1 drink a day, is associated with a lower risk of hypertension, myocardial infarction, stroke, sudden cardiac death, gallstones, cognitive decline, and all-cause mortality. However, even moderate intake places women at higher risk for breast cancer and bone fractures, and higher intake increases risk for colon polyps and colon cancer.

conclusionsRegular alcohol intake has both risks and benefits. In analyses using repeated assessments of alcohol over time and deaths from all causes, women with low to moderate intake and regular frequency (> 3 days/week) had the lowest risk of mortality compared with abstainers and women who consumed substantially more than 1 drink per day.

Indexed as

NursesAdultAlcohol DrinkingEpidemiologic StudiesFemaleHumansLife StyleLongitudinal StudiesMiddle AgedProspective StudiesRisk FactorsUnited StatesWomen's Health

Identifiers

PMID27459455
PMCPMC4981808
OpenAlexW2484113344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.