Trial reportPloS one2016
Effects of Nurse-Led Multifactorial Care to Prevent Disability in Community-Living Older People: Cluster Randomized Trial.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 9 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Effectiveness of Nurse-Led Case Management in Community Settings Among Older Adults: A Systematic Review and Meta-Analysis.International journal of older people nursing · 2026Pooled it
- Community care navigation intervention for people who are at risk of unplanned hospital presentations.The Cochrane database of systematic reviews · 2025Pooled it
- Exploring Nursing Interventions for Frail Individuals in Primary Care: A Systematic Review.International nursing review · 2025Pooled it
- Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis.Health technology assessment (Winchester, England) · 2024Pooled it
- Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2024Pooled it
- Comprehensive Geriatric Assessment for community-dwelling, high-risk, frail, older people.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- Comprehensive geriatric assessment in primary care: a systematic review.Aging clinical and experimental research · 2020Pooled it
- Pooled it
- Trial
- Trial
- Transferability of nurse-led interventions for cardiovascular health across diverse nursing roles in primary and community settings: Practice implications and solutions from a scoping review.American journal of preventive cardiology · 2026Review
- Nurse-Led Interventions Targeting Clinical Correlates of Immunosenescence in Older Adults: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- Integrated Hospital-Territory Organizational Models and the Role of Family and Community Nurses in the Management of Chronic Conditions: A Scoping Review.Medicina (Kaunas, Lithuania) · 2025Article
- A causal loop diagram of older persons' emergency department visits and interactions of its contributing factors: a group model building approach.European geriatric medicine · 2023Article
- Case management for integrated care of older people with frailty in community settings.The Cochrane database of systematic reviews · 2023Review
- Article
- Evidence-based interventions and nurse-sensitive outcomes in district nursing care: A systematic review.International journal of nursing studies advances · 2021Review
- Nursing Care Coordination for Patients with Complex Needs in Primary Healthcare: A Scoping Review.International journal of integrated care · 2021Article
- Addressing safety risks in integrated care programs for older people living at home: a scoping review.BMC geriatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the effects of nurse-led multifactorial care to prevent disability in community-living older people.
methodsIn a cluster randomized trail, 11 practices (n = 1,209 participants) were randomized to the intervention group, and 13 practices (n = 1,074 participants) were randomized to the control group. Participants aged ≥ 70 years were at increased risk of functional decline based on a score ≥ 2 points on the Identification of Seniors at Risk- Primary Care, ISAR-PC. Participants in the intervention group received a systematic comprehensive geriatric assessment, and individually tailored multifactorial interventions coordinated by a trained community-care registered nurse (CCRN) with multiple follow-up home visits. The primary outcome was the participant's disability as measured by the modified Katz activities of daily living (ADL) index score (range 0-15) at one year follow-up. Secondary outcomes were health-related quality of life, hospitalization, and mortality.
resultsAt baseline, the median age was 82.7 years (IQR 77.0-87.1), the median modified Katz-ADL index score was 2 (IQR 1-5) points in the intervention group and 3 (IQR 1-5) points in the control group. The follow-up rate was 76.8% (n = 1753) after one year and was similar in both trial groups. The adjusted intervention effect on disability was -0.07 (95% confidence interval -0.22 to 0.07; p = 0.33). No intervention effects were found for the secondary outcomes.
conclusionsWe found no evidence that a one-year individualized multifactorial intervention program with nurse-led care coordination was better than the current primary care in community-living older people at increased risk of functional decline in The Netherlands.
trial registrationNetherlands Trial Register NTR2653.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.